1 / 8

Presented by Hsin-Yang Li OB/GYN Dept., Taipei VGH

Presented by Hsin-Yang Li OB/GYN Dept., Taipei VGH. Cell fate establishment. (MOORE AND PERSAUD, Before We Are Born, 6th edition). Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways. Induction of activated Ras expression promotes formation of trophoblastic tumors from ES cells.

luann
Download Presentation

Presented by Hsin-Yang Li OB/GYN Dept., Taipei VGH

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Presented by Hsin-Yang Li OB/GYN Dept., Taipei VGH

  2. Cell fate establishment (MOORE AND PERSAUD, Before We Are Born, 6th edition)

  3. Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways

  4. Induction of activated Ras expression promotes formation of trophoblastic tumors from ES cells

  5. Trophoblastic stem cell establishmentfrom Ras-activated ES cells

  6. Ras-MAPK signaling regulates embryonic Cdx2expression and trophoblast differentiation

  7. Blockade of Ras-MAPK signaling leads to a developmental delay of the embryos

  8. Conclusion Ras-MAPK signaling Trophoblast differentiation NATURE GENETICS 40, 921-926 (JULY 2008)

More Related