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Asthma. By: Mohammed Ahmed Sarwar Jaafar Ali Yasser A. Mohammed. Asthma. Impaired breathing due to obstruction and inflammation of airways. Severity vary from shortness of breath to death . . Pathophysiology.
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Asthma By: Mohammed Ahmed Sarwar Jaafar Ali Yasser A. Mohammed
Asthma • Impaired breathing due to obstruction and inflammation of airways. • Severity vary from shortness of breath to death.
Pathophysiology • With exposure to a trigger, a cascade of cellular responses result in: -Increased mucus production -Mucosal swelling -Bronchial muscle contraction
-Smoking -Infections -Allergens • Exercise -Weather -Drugs -Food additives Triggers
Asthma types: • According to the etiology, asthma classified to: • Extrinsic (atopic) asthma • Intrinsic (non-atopic) asthma
Extrinsic asthma • Allergic for substances like: dust, fungi… • Usually onset at young age. • Other allergic manifestation in patients. • Due to genetic susceptibility.
Intrinsic asthma • Non allergic. • Usually adult onset. • Often follows severe respiratory illness.
Nocturnal asthma • Why asthma attack more common at night? • Because: -Core temp. decrease -Sleep homeostat -Circadian change
Signs and symptoms • Different from one person to another. • Symptoms different from one asthma attack to another. • Having symptoms does not mean you have asthma.
Signs and symptoms -shortness of breath -Tightness of chest -Signs of cold and allergens -Feeling very tired
-Coughing after exercise -Blue lips -Trouble sleeping -wheezing & night coughing