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Diabetes Mellitus Type 2. Diabetes Mellitus. Diabetes mellitus is “a group of common metabolic disorders that share the phenotype of hyperglycemia.” (HPIM 17 th ed.)
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Diabetes Mellitus • Diabetes mellitus is “a group of common metabolic disorders that share the phenotype of hyperglycemia.” (HPIM 17th ed.) • “Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces.” (WHO, 2011)
Diabetes Mellitus • Type 2 DM is characterized by insulin resistance and abnormal insulin secretion • According to the WHO, there were 2,770,000 Filipinos with Type 2 DM in 2000 and projects that by 2030, this number will rise to 7,798,000 and the Philippines is going to be in the Top 10 countries with the highest number of people with diabetes.
DM Type 2 Pathophysiology • Abnormal muscle and fat metabolism
DM Type 2 Pathophysiology • Impaired insulin secretion
DM Type 2 Pathophysiology • Increased hepatic glucose and lipid production
DM Type 2 Pathophysiology • Increased hepatic glucose and lipid production
DM Type 2 Pathophysiology • Increased hepatic glucose and lipid production