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Underweight pregnant women in low risk populations: Does a low BMI (<18.5) predict adverse pregnancy outcomes?. Paul de Cock AIRC2012. Midwifery Academy Amsterdam Groningen (AVAG) VU University Medical Center. Echelon system in perinatal care.
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Underweight pregnant women in low risk populations: Does a low BMI (<18.5) predict adverse pregnancy outcomes? Paul de Cock AIRC2012
Midwifery Academy Amsterdam Groningen (AVAG) • VU University Medical Center
Echelon system in perinatal care The Netherlands: echelon system in perinatal care • 1st: community: monitored by independent midwife • 2nd: hospital: gynaecologist & clinical midwife • 3rd: academic referral centre: gynaecologist & clinical midwife http://www.knov.nl/docs/uploads/Midwifery_in_The__Netherlands__20120730__groot.pdf
Midwifery care • App. 184000 births in Netherlands • A quarter of these are home births • Antenatal care by Midwife in 79.6% of pregnancies • Remaining pregnancies (20.4%) are under supervision of gynaecologist (hospital/secondary care) • Half of these are because of a medical indication.
Risk selection in echelons • Women with health complications or known health risks are referred to secondary care setting • This means that there is a risk selection in primary care, which is effective. • For low BMI women this means that only those with no known additional health risks are under supervision of a primary care midwife.
Reason for this research • University of applied science keeps strong links with the field – the field is actively invited to submit research questions to the college • Manager of a large midwifery practice asked about the risks attached to low BMI for pregnant women under supervision of a primary care midwife. • Women with medical indications have been referred. Is there a risk for the remaining healthy low BMI women with regard to pregnancy outcomes for mother and baby?
Low BMI – risk • Increased risk of miscarriage (Maconochie et al., 2007) • Preterm birth (Han et al., 2011) • Low birth weight (Han et al., 2011) • Increased risk of anaemia (Sebire et al., 2007)
Low BMI – lowered risk of… • Reduced risk of complications, such as: • Gestational diabetes mellitus • Pre-eclampsia • Obstetricintervention • Postpartum haemorrhage (Sebire et al., 2007 - BMI<20)
Low BMI in low-risk population • Research question: • What are the pregnancy outcomes of low-risk underweight women in primary midwifery care?
Method - sample • Retrospective case-control database study • 2 large midwifery practices • All underweight (< 18.5) women on record (past 5 years) • Controls matched on age, smoking, alcohol use, drug use • Only controls with normal BMI were included (18.5 – 24.99) • Zwangerschapsuitkomsten: • Zwangerschapsduur • Geboortegewicht
Method - outcomes • Maternal • Hypertension • Hb (1st consult and at 30 weeks) • Suspected intrauterine growth retardation • Birth outcomes • Duration of pregnancy • Prematurity • Instrumental delivery • Bloodloss • Active management of placental delivery
Method - outcomes • Neonatal • Weight • Weight percentile (<2.3; <5.0; <10) • APGAR <7 after 5 minutes • Consult with paediatrician
Discussion • Women with low BMI at increased risk of anaemia. • Babys are smaller, but no raised levels of suspected IUGR, poor APGAR scores or consults with paediatrician. • No difference in prematurity found in this study
Conclusion • On the basis of this study pregancy outcomes do not appear to differ much between women with low and normal BMI in primary care. • More research is being done in a large prospective cohort study (DELIVER) to assess a broader range of outcomes in a large national sample.
Paul de Cock PhD ab, Willemijn Perdijk b, MA RM, Aresh Mohammadi BA RM b, Elise Neppelenbroekb, Ingrid Hollemab Thank you for listening • a Department of Midwifery Science, AVAG and the EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands, p.decock@vumc.nl. • b Midwifery Academy Amsterdam Groningen, The Netherlands; T: +31 50- 3618886, F: + 31 50-3619930,