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Pharma is experience challenges

Pharma is experience challenges. US $ investment hours of work experiments researchers years drug. 1,000,000,000 7,000,874 6587 423 8 1. We want to contribute. Pharma R&D is adapting for the future Focus is on: Productivity, ROI Externalization & Collaboration Diversification

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Pharma is experience challenges

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  1. Pharma is experience challenges US $ investment hours of work experiments researchers years drug 1,000,000,000 7,000,874 6587 423 8 1

  2. We want to contribute • Pharma R&D is adapting for the future • Focus is on: • Productivity, ROI • Externalization & Collaboration • Diversification • Personalized Medicine • Publish • 300,000 articles/yr • 2,000 journals • 20,000 books • Leading titles (e.g. Cell, The Lancet) • Global STM coverage • 18,000 titles used in abstracting, indexing • Extensive patent coverage (USTPO, EPO, WPO) • Dedicated Science, Medical Information company • 7,000 Employees • PhD scientists, information scientists, publishers • Extensive scientific network • 600,000 authors • 300,000 reviewers • 70,000 journal editors and board members

  3. Our information spans Pharma’s value chain Target Finding Target Validation Lead ID Lead Validation Toxicity Safety Phase I Phase II PoC Phase III Phase IV Post Launch Trusted External R&D

  4. Evolving with Pharma R&D • Identify relevant knowledge that drives R&D • Disseminate content to scientists, R&D decision makers • Make content interactive and actionable Creating Insight

  5. Identify relevant content that drives R&D ... the present ... the past

  6. Disseminate Content to Scientists, R&D decision makers ... the present ... the past

  7. Make Content Interactive and Actionable ... The present ... The past

  8. Why is Elsevier here? Because our customers have come here.... Novartis announces USD 1 billion investment to build largest pharmaceutical R&D institute in China Press Release November 2009 ... And our new customers are here

  9. What is Reaxys? • A workflow solution for researchers in chemistry, drug discovery and related scientific areas Using Reaxys researchers can • Easily access validated reaction and substance data, ranking and filtering for relevant results • Source available chemicals • Plan and optimize synthetic route • Export and share results for immediate action in the lab • An extensive repository of reaction and substance property data, Reaxys includes: • Organic, inorganic, organometallic chemistry from 400 journals • Coverage from 1771 - present • World Patent Office, European Patent Office and US English language patents from the major chemistry patent classes

  10. Reaxys extracts valuable chemical properties and reaction details from journals and patents. 1H NMR 300 MHZ

  11. Five good reasons to use Reaxys The wealth of experimentally validated data which can be searched, filtered and ranked to find the most relevant answer to a specific question quickly. Functionality beyond data searching: synthesis planner, results management, smart analysis tools for fast evaluation. No user or usage limits: flat-rate for institution-wide access at any time. The intuitive interface and online educational material help reduce your training efforts. Interoperable: linking to SciVerse Scopus, full-texts at publishers and patent offices. Access to your own library settings via OpenURL resolver is possible. Professor Peter Johnson, University of Leeds

  12. What our customers say: Peter Johnson, University of Leeds Reaxys is used by 24 of the Top-25* ranked academic chemistry research programs Src: 2011 www.arwu.org

  13. Reaxys Case Study: Finding coumarin glycosides

  14. What we will do • Search by structure • Filter By substructure, spectra, and bioactivity • Export to a spreadsheet • Create a Synthesis Plan • Use the Form-based and Advanced Search Tabs • Search by Keyword

  15. O O O HO O O O O Find coumarin glycosides Examples: Isolate the substances that have NMR data and antibacterial activity

  16. coumarin

  17. glucopyranose 5

  18. *bac*

  19. bacterio antibac

  20. *’ palladium catalyst

  21. hydrogenation Reaction type

  22. Coumarin NEXT glycoside C*marin* NEXT glycosid*

  23. What you have seen • Search by structure • Filter By substructure, spectra, and bioactivity • Export to a spreadsheet • Create a Synthesis Plan • Use the Form-based and Advanced Search Tabs • Search by Keyword

  24. Thank You Reaxys training materials can be found at www.reaxys.com/info Contact Reaxys Customer Support at: Usinfo@reaxys.com if you would like to schedule a Reaxys Advanced Training webinar

  25. Thank you • Questions?

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