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siFGFR4

Supplementary Figure S1: FGFR4 silencing synergistically enhances the effects of chemotherapy in colon cancer cells. B. A. Neg Con. FGFR4_2. siFGFR4. FGFR4_6. FGFR4. β Actin. C. D. Supplementary Figure S2: FGFR4 silencing decreasesSTAT3 activity and mRNA expression of FLIP and Bcl-2. A.

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siFGFR4

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  1. Supplementary Figure S1: FGFR4 silencing synergistically enhances the effects of chemotherapy in colon cancer cells. B A Neg Con FGFR4_2 siFGFR4 FGFR4_6 FGFR4 βActin C D

  2. Supplementary Figure S2: FGFR4 silencing decreasesSTAT3 activity and mRNA expression of FLIP and Bcl-2 A 2.5 5 10 Con B Neg Con FGFR4_2 siFGFR4 FGFR4_6 pSTAT3 tSTAT3 Actin C 24Hr 48Hr Con 2.5 5 10 BGJ398 (µM) pSTAT3 tSTAT3 GAPDH

  3. Supplementary Figure S3 FGFR4 silencing in drug resistant colon cancer cell lines. A HCT116 FUR OXR SNR Con Con OXA 5-FU Con 5-FU SN38 Con OXA 5-FU 5-FU OXA FGFR4 Actin

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