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Merck & Co., Inc. : A Leader In Science

Merck & Co., Inc. : A Leader In Science. Michael Cinkala Roanoke College March 29, 2001. A Brief History of the Company. Began in Darmstadt, Germany in 1827 when Emanuel Merck started producing alkaloids and other chemicals 1889: A New York office is established

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Merck & Co., Inc. : A Leader In Science

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  1. Merck & Co., Inc. :A Leader In Science Michael Cinkala Roanoke College March 29, 2001

  2. A Brief History of the Company • Began in Darmstadt, Germany in 1827 when Emanuel Merck started producing alkaloids and other chemicals • 1889: A New York office is established • After World War I, the USA branch broke off and formed Merck & Co.,

  3. Company Information • A research and development company which produces a variety of healthcare products • Based in Whitehouse Station, New Jersey • $40.36 billion in sales during the year 2000 • $6.821 billion in net income in 2000 • Money spent on R&D in 2000: $2.3 billion!

  4. Publications The Merck Index The Merck Veterinary Manual The Merck Manual of Geriatrics The Merck Manual of Medical Information Pharmaceuticals M-M-R II vaccine COMVAX PROPECIA PEPCID ZOCOR The Products and Publications of Merck

  5. Stops the body from converting testosterone into 5-alpha-dihydrotestosterone (DHT) • DHT shrinks follicle size • DHT production tends to increase with age C23H36N2O2

  6. Inhibitor of H2 receptors of the stomach • Reduces gastric secretion and acid levels • in the stomach • Can be given orally or via injection C8H15N7O2S3

  7. A lactone that is quickly changed • to a B-hydroxyacid compound via • hydrolysis • This compound acts as an inhibitor • Of 3-hydroxy-3-methlyglutaryl-coenzyme A • (HMG-CoA) reductase • Without reductase, mevalonate, a • predecessor to cholesterol cannot • be formed. C25H38O5

  8. Questions ?

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