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Community Curation in FlyBase 10 ways that researchers can help improve FlyBase data. Introduction. What is ‘Community Curation’? Annotation/revision of data in FlyBase by fly researchers Why do it? Authors/researchers are the experts in their fields
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Community Curation in FlyBase10 ways that researchers can help improve FlyBase data
Introduction What is ‘Community Curation’? • Annotation/revision of data in FlyBase by fly researchers Why do it? • Authors/researchers are the experts in their fields • Limited number of FlyBase curators, and increasing amount and variety of data being published • Improves FlyBase utility for everyone
Current Methods • Add a relevant publication not in FlyBase • Associate genes with an uncurated publication • Flag data types in an uncurated publication
Current Methods (cont.) 4. Submit corrections to gene model annotations
Current Methods (cont.) 5. Work with FlyBase to revise and improve annotation of a particular subject / data type Recent examples: • GO annotation of ‘hearing genes’ (AGOA group) • rationalization of nomenclature for Traf genes (Leptin and colleagues) • modENCODE data sets • protein interaction data (DPiM)
Current Methods (cont.) 6. Help reduce the number of ’orphan genes’ in FlyBase
Current Methods (cont.) • Use FlyBase gene symbols/names in your papers • Unique identifier (e.g. CG number or FBgn) also useful • Contact FlyBase prior to publication if naming a gene • Contact FlyBase if the FlyBase symbol is ‘wrong’ (e.g. inaccurate, misleading, or doesn’t reflect common usage) Advantages include: • Consistency and clarity between literature and FlyBase • Faster, more accurate curation into FlyBase • Makes automatic curation/linking possible
Current Methods (cont.) • Provide accurate and clear references for alleles, transgenes etc. used in your papers • And/or use FlyBase symbols or another unique identifier (e.g. FBid number) Advantages include: • Faster, more accurate curation into FlyBase • Minimize duplicate Reports in FlyBase • Other researchers know exactly which reagents you’ve used
Current Methods (cont.) 9. Declare the FlyBase and/or Genome Annotation ‘Release’ numbers in your papers
Future Methods 10. Gene Summary wikis (coming soon)
Summary • Add relevant publications to FlyBase • Associate genes with uncurated publications • Flag data types in uncurated publications • Submit revisions to gene models • Work with FlyBase curators to improve specific areas • Annotate / clean up 'gene orphans’ • Use FlyBase symbols in your papers • Provide accurate references for reagents in your papers • Declare FlyBase release numbers in your papers • Contribute to Gene Summary wikis (coming soon)