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a. c. IDH mutation. IDH mut & 1p/19q-intact tumors. CD-CIMP+. CIMP-. CpG sites. CIMP+. NTBT. IDH mut & 1p/19q-deleted tumors. IDH wt & 1p/19q-intact tumors and controls. Samples. b. IDH Mutated. IDH Wild-type. Methylation level.
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a c IDH mutation IDHmut & 1p/19q-intact tumors CD-CIMP+ CIMP- CpGsites CIMP+ NTBT IDHmut & 1p/19q-deleted tumors IDHwt & 1p/19q-intact tumors and controls Samples b IDH Mutated IDH Wild-type Methylation level 2.0 1.0 0 -1.0 -2.0