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Metabolic Energy for Dummies:

Metabolic Energy for Dummies:. A quick look at Cellular Metabolism (Energetics) By Richard Belicek. Introduction : This presentation will cover the general steps that nutrient sources take to be utilized by the body and how energy is created through metabolism. What is Metabolism?.

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Metabolic Energy for Dummies:

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  1. Metabolic Energy for Dummies: A quick look at Cellular Metabolism (Energetics) By Richard Belicek

  2. Introduction: This presentation will cover the general steps that nutrient sources take to be utilized by the body and how energy is created through metabolism.

  3. What is Metabolism? • metabolismdefined: the total chemicalactivity and flow of resources that occurs within an organism’s boundary. • Where does it start?

  4. Nutrient sources from food. • Foods such as steak, pizza, salad, ice cream and chocolate are broken down into these MACROMOLECULES: • Proteins • Fats • Carbohydrates

  5. Macromolecules to Simple Subunits • Proteins = Amino Acids • Fats = Fatty Acids and Glycerol • Carbohydrates = Simple Sugars

  6. Subunits follow metabolic pathways • Amino Acids >Protein catabolism = Acetyl CoA >Gluconeogenesis = Pyruvate • Fatty Acids and Glycerol >Oxidation = Acetyl CoA >Gluconeogenesis = Pyruvate • Simple Sugars (Glucose) >Glycolysis =Pyruvate

  7. Glycolysis The sequence of rxns that convert glucose into pyruvate

  8. Glycolysis • Occurs in the Cytoplasm • Aerobic or Anaerobic • Glucose enters the glycolytic pathway • ATP: gross= 4, net= 2 • NAD = 2 NADH, transported to the Electron Transport Chain (ETC)

  9. The Krebs Cycle aka: Tricarboxcyclic Acid Cycle or Citric Acid Cycle.

  10. Krebs Cycle • Pyruvate enters cycle • 2 cycles per Pyruvate molecule • 1 ATP is produced per cycle • NAD and FAD = 6 NADH and 2 FADH2 • NADH and FADH2 are transported to the (ETC)

  11. Electron Transport Chain

  12. Electron Transport Chain • Occurs in the Cristea of the mitochondria • NADH and FADH2 are oxidized • Hydrogen and electrons are carried along chain transfer energy • Electrochemical gradient = ATP • O2 final acceptor = H2O

  13. Electron Transport Chain • (1 NADH= 3 ATP, 1 FADH2 = 2 ATP) • Krebs Cycle = 8 NADH = 24 ATP • = 2 FADH2 = 4 ATP • For glycolysis (1 NADH= 2 ATP) • Glycolysis = 2NADH = 4 ATP

  14. Overview:

  15. Summary • Glycolysis • Krebs Cycle • Electron Transport Chain • Total ATP = 36 net

  16. NO Questions, Thank you.

  17. HOORAY!

  18. Thank you Have a good break!!

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