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„ZUSAMMENARBEIT – Gesundheit“ und „Forschung zugunsten kleiner und mittlerer Unternehmen (KMUs)“

„ZUSAMMENARBEIT – Gesundheit“ und „Forschung zugunsten kleiner und mittlerer Unternehmen (KMUs)“ im 7. EU-Rahmenprogramm Ylva Huber Bereich Europäische und Internationale Programme FFG – Österreichische Forschungsförderungsgesellschaft. Das 7. Rahmenprogramm im Überblick

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„ZUSAMMENARBEIT – Gesundheit“ und „Forschung zugunsten kleiner und mittlerer Unternehmen (KMUs)“

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  1. „ZUSAMMENARBEIT – Gesundheit“ und „Forschung zugunsten kleiner und mittlerer Unternehmen (KMUs)“ im 7. EU-Rahmenprogramm Ylva Huber Bereich Europäische und Internationale Programme FFG – Österreichische Forschungsförderungsgesellschaft

  2. Das 7. Rahmenprogramm im Überblick Themen der ersten Ausschreibungen zu „Gesundheit“ Forschung zugunsten kleiner und mittlerer Unternehmen (KMU) Inhalt

  3. Das 7. Rahmenprogramm im Überblick Themen der ersten Ausschreibungen zu „Gesundheit“ Forschung zugunsten kleiner und mittlerer Unternehmen (KMU) Inhalt

  4. Instrumente im 7. RP

  5. Die Ausschreibungen sind geöffnet! rp7.ffg.at Präsentationstitel der FFG

  6. Das 7. Rahmenprogramm im Überblick Themen der ersten Ausschreibungen zu „Gesundheit“ Forschung zugunsten kleiner und mittlerer Unternehmen (KMU) Inhalt

  7. Ziele: • Verbesserung der Gesundheit der europäischen Bevölkerung • Stärkung der europ. Industrie/Firmen im Bereich Gesundheit • Blick auf globale Gesundheitsfragen (z.B. Epidemien Schwerpunkte: • Translationale Forschung (Grundlagenforschung  klinische Anwendung) • Neue Therapien (Entwicklung und Validierung) • Methoden zur Gesundheitsförderung, Krankheitsprävention • Diagnostische Instrumente und medizinische Technologien • Effiziente Gesundheitssysteme Thema 1- Gesundheit (6.050 Mio. Euro)

  8. 1 Biotechnology, generic tools and technologies for human health 2 Translating research for human health 3 4 Optimising the delivery of health care to European Citizens Other Actions across the Health Theme Thema 1: Gesundheit (6.050 Mio. €) Einreichfrist 1. Ausschreibung: 19. April 2007 Einreichfrist 2. Ausschreibung: 18. September 2007

  9. 1 Biotechnology, generic tools and technologies for human health (1) High-throughput research • Unifying human and model organism genetic variation databases • Temporal and spatial proteomics to study biological processes relevant to human health • Groundbreaking techniques for DNA sequencing and genotyping 2. Call: • SME-driven collaborative research projects for developing tools and technologies for high-throughput research Detection, Diagnosis and Monitoring • Development of a hybrid imaging system • Novel optical methodologies for detection, diagnosis and monitoring of disease or disease-related processes • Novel targeted imaging probes for early in vivo diagnosis and/or evaluation of response to therapy • In vivo image-guidance for cell therapy 2. Call : • Standardisation and improvement of pre-analytical procedures for in vitro diagnostics • High throughput molecular diagnostics in individual patients for genetic diseases with heterogeneous clinical presentation

  10. 1 Biotechnology, generic tools and technologies for human health (2) Predicting suitability, safety and efficacy of therapies Thema zum Großteil durch Innovative Medicines Initiative (IMI) abgedeckt! • Novel alternative testing strategies for use in pharmaceutical discovery and development • Bottlenecks in reduction, refinement and replacement of animal testing in pharmaceutical discovery and development • Promotion, development, validation, acceptance and implementation of QSARs (quantitative structure-activity relationship) for toxicology • Alternative testing strategies for the assessment of the toxicological profile of nanoparticles used in medical diagnostics • In silico modelling for ADMET outcomes

  11. 1 Biotechnology, generic tools and technologies for human health (3) Innovative therapeutic approaches and interventions • Development and production of new generation antibodies • Innovative approaches for the development of vaccines for young children • Immunotherapy of human food allergies 2.Call: • Development of emerging gene therapy tools and technologies for clinical application • Stem cell lines forcell-based therapies. • Development of stem cell culture conditions. • Stem cells for kidney regeneration. • Adding value to EU stem cell therapy research: scientific communication and future perspectives.

  12. 2 Translating research for human health (1) 2.1. INTEGRATING BIOLOGICAL DATA AND PROCESSES LARGE-SCALE DATA GATHERING, SYSTEMS BIOLOGY Large-scale data gathering • Networking biobanking initiatives across Europe: developing standards and norms for existing and future human sample biobanks • Molecular epidemiological studies in existing well characterised European (and/or other) population cohorts • Comparative studies of genetic variation in humans: towards a reference population in Europe • Characterisation and variability of the microbial communities in the Human Body • Structure-function analysis of membrane-transporters and channels for the identification of potential drug target sites • High throughput analysis of lipids and lipid-protein interactions • Genome-wide association studies in mammalian non-rodent models for the identification of genes relevant to human health and disease

  13. 2 Translating research for human health (2) 2.1. INTEGRATING BIOLOGICAL DATA AND PROCESSES LARGE-SCALE DATA GATHERING, SYSTEMS BIOLOGY • Systems biology • A system approach to eukaryotic unicellular organism biology • Modelling of T-cell activation • Fundamental approaches to stem cell differentiation • Developing an integrated in vitro, in vivo and systems biology modelling approach to understanding apoptosis in the context of health and disease 2. call: • Multidisciplinary fundamental genomics and molecular biology approaches to study basic biological processes relevant to health and diseases • Coordination and Support Actions in large-scale data gathering and systems biology • Traditional Chinese Medicine in post-genomic era. Specific International Cooperation Action. Targeted region: China.

  14. 2 Translating research for human health (3) 2.2. RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN DEVELOPMENT AND AGEING Brain and related diseases • Stroke and mechanisms underlying ischemic brain damage • Coding in neuronal assemblies • Neurobiologyof anxiety disorders • Memory loss: underlying mechanisms and therapy • From basic spinal mechanisms to spinal cord disease and trauma. • Neuron-glia interactions in health and disease 2. Call: • Restorative approaches for therapy of neurodegenerative diseases. • From mood disorders to experimental models. • Neuronal mechanisms of vision and related diseases. • Childhood and adolescent mental disorders. Specific International Cooperation Action. Target regions: Eastern Europe and Central Asia and Western Balkans.

  15. 2 Translating research for human health (4) 2.2. RESEARCH ON THE BRAIN AND RELATED DISEASES, HUMAN DEVELOPMENT AND AGEING Human Development and Ageing • Novel approaches to reconstitute normal immune function at old age. • Termination of developmental processes and their reactivation in adult life • Biomarkers of ageing. • Increasing the participation of elderly in clinical trials. • Research on human development and/or healthy ageing across the EU

  16. 2 Translating research for human health (5) 2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES: TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH Anti-microbial drug resistance including fungal pathogens 2. Call: • Novel targets for drugs against Gram negative bacteria. • Host-pathogen interactions in infections by Streptococcus pneumoniae. • An integrated platform for development and clinical evaluation of point-of-care diagnostic devices for microbial detection, antibiotic susceptibility determination and biomarkers • Molecular epidemiology to control nosocomial and community spreading of highly virulent multi-drug resistant strains of bacterial pathogens. • Health and economic cost of antimicrobial resistance. • Conference on genetic and biochemical tools for postgenomic physiological analysis of Staphylococcus, in particular MRSA.

  17. 2 Translating research for human health (6) 2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES: TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH HIV, AIDS, malaria and tuberculosis • HIV/AIDS Drug Discovery and Preclinical Development • Highly innovative approaches for research into host-pathogen interaction in tuberculosis • Development of fast tests for the diagnosis of Multi-Drug-Resistant strains of HIV, malaria and tuberculosis and of latent tuberculosis infection (LTBI). • Addressing knowledge gaps in pregnancy malaria. • New HIV Vaccines inducing broadly-reactive neutralising antibodies. • 2. Call: • Network on HIV and anti-HIV drug resistance • HIV and Hepatitis co-infection • Blocking the transmission of malaria: the mosquito vector target. • European network for study and clinical management of TB drug resistance. • Support platform for the development of PRD vaccines • Highly innovative research in HIV/AIDS, malaria and tuberculosis between Indian and European partners. (SICA, Targeted Region: India) • Coordination of European research activities with global initiatives, including Public-Private-Partnerships (SICA; Targeted Regions: ICPC). • Next generation of researchers for HIV/AIDS, malaria, tuberculosis and neglected infectious diseases (SICA; Targeted Regions: ICPC).

  18. 2 Translating research for human health (7) 2.3. TRANSLATIONAL RESEARCH IN MAJOR INFECTIOUS DISEASES: TO CONFRONT MAJOR THREATS TO PUBLIC HEALTH Potentially new and re-emerging epidemics • Development of broadly protective influenza vaccine candidates. • Identifying immunological mechanisms of protection for influenza vaccines • Standardisation of immunological assays including surrogate markers for evaluation of new influenza vaccines in clinical trials • Innovative point-of-care diagnostic tests for influenza. • Development of additional treatment strategies for patients suffering from highly pathogenic influenza. • Development of pandemic influenza containment and mitigation strategies. • Supporting highly innovative inter-disciplinary research on influenza. • Influenza research in collaboration with Asian partners. (SICA, Targeted regions: Asia) • 2. Call: • Strengthening research on prediction, identification, modelling and surveillance of newly emerging infectious diseases in humans. • Definition of research needs and priorities in Europe in the area of Emerging Infectious Epidemics.

  19. 2 Translating research for human health (8) TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES Cancer • Translating the knowledge on non-coding RNAs linked to the aetiology of cancer into novel diagnosis and therapy strategies. • Translating clinical ’omics’-technology (genomics, proteomics, metabolomics) into innovative cancer biomarkers aiding in early diagnosis, prognosis and treatment selection of cancer patients. • Genomic instability and genomic alterations in pre-cancerous lesions and/or cancer. • Novel cancer screening methods. • Optimising research on end of life care of cancer patients. • Understanding and fighting metastasis. • Improving targeted drug delivery to cancer cells for cancer therapeutics other than gene therapy • Developing high-throughput bioassays and models for human cancers in lower species. • 2. Call: • Innovative combination clinical trials for multimodal cancer therapy. • Role of inflammation in tumour initiation and progression. • Epidemiology of gene-environment interactions involved in carcinogenesis. • Translating the hypoxic tumour microenvironment. • ERA-NET on optimisation of the use of cancer registries for cancer research purposes • Studying cancer aetiology in Latin America. (SICA)

  20. 2 Translating research for human health 9) TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES Cardiovascular Disease • Molecular basis of the inflammatory response and associated vascular remodelling in arteriosclerosis. • Vascular remodelling in aneurysmal disease. • Combating stroke. 2. Call: • Congenital pathologies affecting the heart. • Cell therapies for the treatment of heart ischemia. • Organ imaging in CVD. • Integrating pharmacogenomic approaches into the treatment of CVD.

  21. 2 Translating research for human health 10) TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES Diabetes and Obesity • Early processes in the pathogenesis of type 1 diabetes and strategies for early prevention. • Combined forms of diabetes in children. • Insulin resistance as a key factor in the development of diabetes and metabolic syndrome. • Pathophysiological mechanisms related to excess fat. • A road-map for diabetes research. 2. Call: • Nutritional signals and the development of new diabetes/obesity therapeutic agents. • Markers and treatment for diabetic neuropathy complications. • Geno- and phenotypical differentiation of type 2 subjects and monogenic subjects. • Use of beta cell imaging in diabetes mellitus.

  22. 2 Translating research for human health 11) TRANSLATIONAL RESEARCH IN OTHER MAJOR DISEASES Rare Diseases • Natural course and pathophysiology of rare diseases. • Research capacity-building in the field of rare diseases. Other Chronic Diseases • Osteoarthritis. • Inflammatory bowel disease. • Osteoporosis: signalling pathways in bone formation and homeostasis. • Genetic factors of Osteoporosis. • Intervertebral disc degeneration: prevention and repair. • Innovative concepts in chronic obstructive pulmonary disease pathogenesis (COPD). • Hearing impairment and degeneration. • Impairment of touch and proprioception at old age. • Visual impairment and degeneration. 2. Call: • Understanding and combating age-related muscle weakness. • Translational research aiming for a treatment of urinary incontinence. • Early processes in the pathogenesis of chronic inflammatorydiseases.

  23. 3 Optimising the delivery of health care to European Citizens (1) Translating clinical research into clinical practice including better use of medicines, and appropriate use of behavioural and organisational interventions and health therapies and technologies 2.call: • Implementation of research into healthcare practice • Self-medication and patient safety • Patient Safety Research Network • Improving clinical decision making • Better use of medicines. • Continuity of clinical care. • Patient self-management of chronic disease. Quality, solidarity and sustainability of health systems 2.call: • Evaluation of disease management programmes • Health systems and long term care of the elderly • Mobility of health professionals • Health care human resource planning in nursing. • Clinician working time and patient safety. • Health outcome measures and population ageing. • Trends of population health • European system of Diagnosis-related groups (DRG)

  24. 3 Optimising the delivery of health care to European Citizens (2) Enhanced health promotion and disease prevention 2.call: • Promoting healthy behaviour in children and adolescents • Interventions addressing the gradient of health inequalities • Public health interventions addressing the abuse of alcohol. • Evaluation of suicide prevention strategies across and within European countries. • Improve vaccination coverage Horizontal Coordination and Support Actions across “Optimising the Delivery of Health Care to European Citizens 2.call: • Disease networks of centres of reference. • Effectiveness of health investments. • Patient mobility and access to information. • Brokering research into policy. • A road-map for ageing research. • Health Services Research conference • Mental health research conference. • Public Health intervention research conference

  25. 3 Optimising the delivery of health care to European Citizens (3) Specific International Cooperation Actions for Health System Research 2.call: • Epidemiological investigations into long-term trends of population health as consequence of socio-economic transitions, including life-style induced health problems. SICA (Mediterranean Partner countries, Russia, Eastern European and Central Asia) • Universal and equitable access tohealth care and health financing. SICA (MCP, ACP, Asia and Latin America) • Health care intervention research – optimising hospital care. SICA (Western Balkans.) • Health care intervention research – improving pre-natal and maternal care. SICA (ACP and Mediterranean Partner Countries)

  26. 4 Other Actions across the Health Theme Coordination and Support Actions across the Theme • Reinforcing the network of National Contact Points (NCP) for the Seventh Framework Programme under Health Theme by promoting transnational co-operation.) • Promoting participation of high-technology research intensive SMEs, operating in the biomedical engineering and other medical technology sectors´relevant to Health Theme. • Assessment and valorisation of project outcome for hightechnology and research intensive SME participating to Framework Programmes of Research in the healthcare sector. • Science communication actions. • Initiatives to foster dialogue and debate on health research issues of interest to the public. • Studies on the impact of EU legislation on health research and related developments and applications. • 2.call: • Promotion and facilitation of international cooperation in areas relevant to the objectives of this theme. (SICA, ICPC) Responding to EU policy needs (2.call) • Paediatric medicinal products, Drug safety research, Living and work conditions, Health statistics, Tobacco Control

  27. Technologieplattformen und Gemeinsame Technologieinitiativen • Mobilisierung europäischer Ressourcen im Bereich Forschung, technologische Entwicklung und Innovation durch Zusammenbringen aller Akteure eines definierten Forschungsbereiches (Industrie, KMU, Universitäten, Endverbraucher) • Industriegetrieben • Gemeinsame Definition und Erstellung einer strategischen Forschungsagenda (mittel- bis langfristig) = Input zur Entwicklung der thematischen Programme im 7. RP • Einige wenige werden als Gemeinsame Technologieinitiativen (Joint Technology Initiatives) etabliert • Neuer Weg zur Realisierung von public-private partnerships auf EU-Ebene mit definierter rechtlicher Struktur

  28. Example „Innovative Medicines“ - en route to a „Joint Technology Initiative“ • Accelerated Development of safe and more effective medicines • Revitalization of the the biopharmaceutical research and development (R&D) environment for Europe to become more competitive • Improving the collaboration between all relevant actors from public and private organisations (public-private partnerships) • Draft and Implementation of a European Research Agenda: Second version of the Strategic Research Agenda published recently • First Calls expected for end of2007/beginning of 2008 • http://europa.eu.int/comm/research/fp6/index_en.cfm?p=1_innomed • http://rp7.ffg.at/RP7.aspx_param_target_is_116120.v.aspx

  29. « Innovative Medicines » 2. version of the « Strategic Research Agenda »: 4 main topics: • Safety: Early safety evaluation and risk assessment, creation of a European Centre for Drug Safety • Efficacy: Predictive pharmacology, biomarker identification and validation, patient recruitment and risk assessment • Knowledge Management: New technologies to control and analyse enormous quantities of information in an integrative and predictive way • Education and Training: Bridge gaps in expertise required to strengthen the biopharmaceutical R&D process, creation of a European Medicines Research Academy

  30. Technologieplattform « Innovative Medicines » • Contact in Austria: Univ. Prof. Dr. Hans Georg Eichler, Vice Rector of the Medical University in Vienna vr_forschung@meduniwien.ac.at

  31. Food, Agriculture, Fisheries and Biotechnology: e.g. Fork to farm: Food (including seafood), health and well being Information and Communication Technologies: Objective ICT-2007.5.3: Virtual Physiological Human Nanosciences, Nanotechnologies, Materials and new Production Technologies: „Creation of a critical and commented database on the health, safety and environmental impact of nanoparticles“ „Substantial innovation in the European medical industry: development of nanotechnology-based systems for in-vivo diagnosis and therapy (in Coordination with topic HEALTH-2007-2.4.1-7 and HEALTH-2007-1.2-3 in Theme 1 "Health") Environment: Environment and Health Security: Topic SEC-2007-1.3-05 Water distribution surveillance; Critical Infrastructure Protection Relevante Themen der 1.Ausschreibungen aus anderen Bereichen

  32. Das 7. Rahmenprogramm im Überblick Themen der ersten Ausschreibungen zu „Gesundheit“ Forschung zugunsten kleiner und mittlerer Unternehmen (KMU) Inhalt

  33. Zusammenarbeit zwischen Industrie und F&E-Dienstleistern • Forschung zugunsten von Kleinen und Mittleren Unternehmen (KMUs) • Forschung zugunsten von KMU-Verbänden Präsentationstitel der FFG

  34. Kennzeichen • Themen: Bottom up –Ansatz (gesamtes Feld der Wissenschaft & Technologie) • KMUs/KMU-Verbände lagernForschung & technologische Entwicklung aus • Flexibilität bezüglich der intellectual property rights Präsentationstitel der FFG

  35. Aktivitäten • Forschungs- und technologische Entwicklungsaktivitäten • Demonstrationsaktivitäten • Andere Aktivitäten (Trainings, dissemination activities) • Management-Aktivitäten Präsentationstitel der FFG

  36. Research for SMEs Project participation scheme RTD-performers Industry at least 2 universities research centres industrial companies research performing SMEs at least 3 SMEs from at least 3 countries (MS, AS) Präsentationstitel der FFG

  37. Research for SMEs/SME-Associations * Share of R&D carried out by RTD performers : ≥ 60% Source: European Commission Präsentationstitel der FFG

  38. Einreichfristen: • Research for SMEs: FP7-SME-2007-1 • Einreichfrist: 4.September 200 • Research for SME Associations: FP7-SME-2007-2 • Einreichfrist: 1. Juni 2007 • Kontakt: Dr. Ines Haberl, ines.haberl@ffg.at • http://rp7.ffg.at/RP7.aspx • http://cordis.europa.eu/en/home.html Präsentationstitel der FFG

  39. Wichtige Dokumente zur Vorbereitung: • Arbeitsprogramme + Annexes • Guide for Applicants • Rules for Participation • Model Grant Agreement • Leitfaden/Formular für Anbahnungsfinanzierung: rp7.ffg.at -> „Services der FFG“

  40. Kontaktieren Sie uns!Ihre Ansprechpartner für Life Sciences in der FFG/Bereich Europäische und InternationaleProgramme Mag. Birgit Steininger Leiterin des Referats für Biowissenschaften, Nationale Kontaktstelle für Lebensmittel, Landwirtschaft und Biotechnologie (DW 4101) birgit.steininger@ffg.at Dr. Ylva Huber Nationale Kontaktstelle für Gesundheit (DW 4102) ylva.huber@ffg.at Dr. Ines Haberl Nationale Kontaktstelle für KMUs (DW 4103) Ines.haberl@ffg.at e-mail: vorname.nachname@ffg.at, Tel: +43/57755-Durchwahl

  41. Vielen Dank für Ihre Aufmerksamkeit&viel Erfolg für Ihre Projekte im 7. Rahmenprogramm!

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