1 / 7

Colorectal Cancer Prevention & Early Detection : Update 2008

Colorectal Cancer Prevention & Early Detection : Update 2008. American Cancer Society. Risk Factor - Polyps. Different types: Hyperplastic minimal cancer potential Adenomatous approximately 90% of colon and rectal cancers arise from adenomas.

magee
Download Presentation

Colorectal Cancer Prevention & Early Detection : Update 2008

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Colorectal Cancer Prevention & Early Detection:Update 2008 American Cancer Society

  2. Risk Factor - Polyps Different types: • Hyperplastic • minimal cancer potential • Adenomatous • approximately 90% of colon and rectal cancers arise from adenomas

  3. Trends in Recent* Endoscopy Prevalence (%), by Educational Attainment and Health Insurance Status, Adults 50 Years and Older, US, 1997-2004 *A flexible sigmoidoscopy or colonoscopy within the past five years. Note: Data from participating states and the District of Columbia were aggregated to represent the United States. Source: Behavioral Risk Factor Surveillance System CD-ROM (1996-1997, 1999) and Public Use Data Tape (2001, 2002, 2004), National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention and Prevention, 1999, 2000, 2002, 2003, 2005.

  4. Trends in Recent* Fecal Occult Blood Test Prevalence (%), by Educational Attainment and Health Insurance Status, Adults 50 Years and Older, US, 1997-2004 *A fecal occult blood test within the past year. Note: Data from participating states and the District of Columbia were aggregated to represent the United States. Source: Behavioral Risk Factor Surveillance System CD-ROM (1996-1997, 1999) and Public Use Data Tape (2001, 2002, 2004), National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention and Prevention, 1999, 2000, 2002, 2003, 2005.

  5. CRC Screening Guidelines: What’s New? CRC screening tests are grouped into two categories: • Tests that detect cancer and precancerous polyps* • Tests that primarily detect cancer * It is the strong opinion of the consensus guidelines group that colon cancer prevention should be the primary goal of CRC screening. • Exams that are designed to detect both early cancer and precancerous polyps should be encouraged if resources are available and patients are willing to undergo an invasive test • If the full range of screening tests are not available, physicians should make every effort to offer at least one test from each category

  6. 2-D view 3-D view Polyp CT Colonography Polyp Courtesy of Beth McFarland, MD

  7. Normal Epithelium LateAdenoma Early Cancer Late Cancer Adenoma Genetic Model of Colorectal Cancer Bat-26 (Sporadic) p53 Bat-26 (HNPCC) K-ras APC Mutation Dwell Time: Many decades 2-5 years 2-5 years Optimum phase for early detection Courtesy of Barry M. Berger. MD, FCAP EXACT Sciences

More Related