nrclinonc.2012.61-pf2

Sep 19, 2014

10 likes | 103 Views

Figure 2 Comparison of genome-wide gene-expression profiles between primary patient tumours and PDTX tumours. Tentler, J. J. et al. ( 2012) Patient-derived tumour xenografts as models for oncology drug development Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2012.61.

Share Presentation

Embed Code

Link

tentler
pdtx tumours
1038 nrclinonc
doi 10
primary patient tumours
oncology drug development

mahdis

Download Presentation

nrclinonc.2012.61-pf2

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

Figure 2Comparison of genome-wide gene-expression profiles between primary patient tumours and PDTX tumours Tentler, J. J. et al.(2012) Patient-derived tumour xenografts as models for oncology drug development Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2012.61

nrneph.2012.214-pf2

Figure 2 Recovery of renal function is better with a shorter interval between onset of aHUS and initiation of eculizumab. Zuber, J. et al. (2012) Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies Nat. Rev. Nephrol. doi:10.1038/nrneph.2012.214.

158 views • 1 slides

nrclinonc.2010.37-pf1

Figure 1 Comparison of a | PFS and b | overall survival curves from the JGOG study on dosedense therapy 1 and the GOG study on IP therapy. Thomas Hogberg (2010) Current drugs still have potential in advanced ovarian cancer Nat. Rev. Clin. Oncol. doi:10.1038/nrclinonc.2010.37.

103 views • 1 slides

nrendo.2013.227-pf2

Figure 2 Genotype frequencies for rs17817964 within and across ancestries based on the 1000 Genomes Project. Loos, R. J. F. & Yeo, G. S. H. (2013) The bigger picture of FTO —the first GWAS‑identified obesity gene Nat. Rev. Endocrinol. doi:10.1038/nrendo.2013.227.

180 views • 1 slides

nrendo.2013.64-pf2

Figure 2 Schematic representation of potential depot-specific differences between subcutaneous and visceral adipose tissue in mice with normal GH signalling, low GH signalling (such as Ghr –/– mice) or increased GH signalling (such as GH transgenic mice).

141 views • 1 slides

nrcardio.2013.158-pf2

Figure 2 The role of TEE in determining suitability of mechanical LAA occlusion and in guiding device sizing. Yu, C.‑M. et al. (2013) Mechanical antithrombotic intervention by LAA occlusion in atrial fibrillation Nat. Rev. Cardiol. doi:10.1038/nrcardio.2013.158.

126 views • 1 slides

ncpendmet0594-pf2

Figure 2 Examples of whole body scans and whole body radioiodine retention either after administration of rhTSH or after THW.

76 views • 1 slides

ncponc0059-pf2

Figure 2 MRI scan obtained 2 weeks after admission and 1 week after initiation of corticosteroid therapy. Plotkin, SR et al. (2005) Facial numbness in a man with inguinal and retroperitoneal masses . Nat Clin Pract Oncol 2 : 54 – 58 10.1038/ncponc0059.

197 views • 1 slides

ncpuro0184-pf2

Figure 2 Polysomnography (hypnogram) coupled with penile tumescence recordings demonstrate three episodes of rapid eye movement sleep-related erection with pain and awakening. Karsenty G et al . (2005) Sleep-related painful erections Nat Clin Pract Urol 2: 256 –260 doi:10.1038/ ncpuro0184.

200 views • 1 slides

ncpneuro0804-pf2

Figure 2 A brain biopsy specimen stained with hemotoxylin and eosin showed foci of microglia and lymphocytes involving the leptomeninges and neuropil. Valcour V et al . (2008) A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia

129 views • 1 slides

ncpgasthep0871-pf2

Figure 2 Factors influencing differential diagnoses of drug-related hepatitis in individuals with elevated levels of aspartate aminotransferase, alanine aminotransferase,  -glutamyltransferase, alkaline phosphatase and bilirubin (both conjugated and unconjugated).

169 views • 1 slides

nrgastro.2009.203-pf2

Figure 2 Kaplan–Meier curves from a Norwegian population-based study showing influence of MH on outcomes in patients with IBD.

134 views • 1 slides

ncponc0820-pf2

Figure 2 The proteins involved in the RB1 and p53 pathways with some interactions with the P13K/PKB pathway. Collins VP (2007) Mechanisms of Disease: genetic predictors of response to treatment in brain tumors Nat Clin Pract Oncol 4 : 362 –374 doi:10.1038/ncponc0820.

89 views • 1 slides

nrrheum.2013.197-pf2

Figure 2 Suggested algorithm for assessment, monitoring and management of patients with RA‑ILD on biologic therapy. Jani, M. et al. (2013) The safety of biologic therapies in RA‑associated interstitial lung disease Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2013.197.

160 views • 1 slides

nrm2104-pf2

Garneau et al. Nature Reviews Molecular Cell Biology 8 , 113 – 126 (February 2007) | doi:10.1038/nrm2104.

103 views • 1 slides

nrm1835 pf2

Thiery et al. Nature Reviews Molecular Cell Biology 7 , 131 – 142 (February 2006) | doi:10.1038/nrm1835.

117 views • 1 slides

nrgastro.2009.20 pf2

Figure 2 A CT scan of a patient with a massive pseudocyst of the pancreas that compressed not only the stomach but also the duodenum. O'Keefe SJD (2009) A guide to enteral access procedures and enteral nutrition Nat Rev Gastroenterol Hepatol doi:10.1038/nrgastro.2009.20.

142 views • 1 slides

nrclinonc.2010.19 pf1

Figure 1 Forrest plot showing pooled data for a | incidence of clinical fractures and b | incidence of breast cancer recurrence from the Z‑FAST, ZO‑FAST and EZO‑FAST studies.

80 views • 1 slides

nrneurol.2014.178 pf2

Figure 2 Spatial patterns of task-free networks commonly investigated in neurodegenerative disorders. Pievani, M. et al. (2014) Brain connectivity in neurodegenerative diseases—from phenotype to proteinopathy Nat. Rev. Neurol. doi:10.1038/nrneurol.2014.178.

158 views • 1 slides

nrendo.2013.246 pf2

Figure 2 Transversal CT image of a typical small-bowel neuroendocrine tumour mesenteric metastasis (arrow). van Essen, M. et al. (2013) Neuroendocrine tumours: the role of imaging for diagnosis and therapy Nat. Rev. Endocrinol. doi:10.1038/nrendo.2013.246.

140 views • 1 slides

nrneph.2012.249 pf2

Figure 2 The aldosterone paradox. Aldosterone exerts differential effects during hypovolaemia and hyperkalaemia. Sevá Pessôa, B. et al . (2012) Key developments in renin–angiotensin–aldosterone system inhibition Nat. Rev. Nephrol. doi:10.1038/nrneph.2012.249.

387 views • 1 slides

nrneph.2012.213 pf2

Figure 2 Activation of C3 convertase is involved in both complement-mediated and immune-complex-mediated MPGN. Bomback, A. S. & Appel, G. B. (2012) Pathogenesis of the C3 glomerulopathies and reclassification of MPGN Nat. Rev. Nephrol. doi:10.1038/nrneph.2012.213.

225 views • 1 slides

ncpneuro0605 pf2

Figure 2 Periodic discharges of nonconvulsive status epilepticus following convulsive status epilepticus. Korff CM and Nordli DR (2007) Diagnosis and management of nonconvulsive status epilepticus in children Nat Clin Pract Neurol 3: 505 –516 10.1038/ncpneuro0605.

151 views • 1 slides

More Related