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Neurotransmitter Storage and Release

VGCC. CaM. K. +ATP. P. P. Ca 2+ -CaMK. -P. P. P. -P. P. P. P. P. Neurotransmitter Storage and Release. Eric Niederhoffer SIU-SOM. Ca 2+. Ca 2+ -CaM. ……….. ……….. ……….. ……….. ………. ……….. ……….. ……….. ……….. ………. NT. Botulinum and Tetanus toxin.

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Neurotransmitter Storage and Release

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  1. VGCC CaM K +ATP P P Ca2+-CaMK -P P P -P P P P P Neurotransmitter Storage and Release Eric Niederhoffer SIU-SOM Ca2+ Ca2+-CaM ……….. ……….. ……….. ……….. ………..

  2. ……….. ……….. ……….. ……….. ……….. NT Botulinum and Tetanus toxin Storage and release complex Docking and fusion complex Synp Synt Synb VAMP SNAP 23 25 Synx Nr Ca2+ Vesicle Fusion VT Ac Syn CaMK v-SNARE Rab3 t-SNARE

  3. Review Questions • How are neurotransmitters packaged and released (signal transduction pathway, second messenger, transporters, receptors)?

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