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STAT ( Ememgent ) EEGs. Nonconvulsive Status Epilepticus. Emergency – pathological condition which is life threatening or which can lead to organ failure requiring prompt treatment in order to avoid severe worsening and/or severe sequels. STAT. From Latin statim - immediately. Problems.
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STAT (Ememgent) EEGs Nonconvulsive Status Epilepticus
Emergency – pathological condition which is life threatening or which can lead to organ failure requiring prompt treatment in order to avoid severe worsening and/or severe sequels Neurophysiologie Clinique 1998
STAT • From Latin statim- immediately
Problems • Poor use of time and resources • Detriment of patients who really need stat procedures • Increased turnaround time of non-STAT procedures • Staffing difficulties • Increasing use of overtime • Frustration and strain on staff and physicians • STAT EEG is not like STAT EKG Benbadis 2008
Performed emergently • Interpreted emergently • Acted upon emergently
256 emegent EEGs (total 2798 EEGs) • Useful helped in diagnosis, therapy or exclusion of specific condition • Corroborative • Not useful Khan et al., Clin Neurophysiol 2005
Epilepsy related indictions(status epilepticus and followup, recurrent seizures, nonconvulsive status) – 93% useful • Other conditions – 52.6% useful Khan et al., Clin Neurophysiol., 2005
111 consecutive eEEGs • Change in treatment – 37.8% Praline et al. 2007
32 emergent pediatric EEGs (1.8 % of total) • Useful in decision making 30/32 (94 %) • Neurologist approved all of studies Kothare et al. J Child Neurol 2005
Comparison of NCSE (12) and non-NCSE (36) • Duration of symptoms • Remote risk factors* • Recent risk factors • Tonic-clonic activity in current episode • History of epilepsy • Mental state/Glasgow coma scale* • Ocular movement abnormalities* • Subtle motor abnormalities Husain et al., JNNP 2002
Remote risk factors • Previous stroke • Previous neurosurgery • Tumor • Dementia • Meningitis Husain et al. JNNP 2002
Eye movement abnormalities • Nystagmoid eye jerks • Hippus • Repeated blinking • Persistent eye deviation Husain et al., JNNP 2002
78 emergent EEGs • 8 NCSE • Risk factors • History of epilepsy • Observed GTCS • Seizure-like motor activity R. Khan, J Natl Med Assn, 2001
All patients (8) with NCSE had at least one risk factor • 35 patients had at least one risk factor • 43 patients had no risk factors – none had NCSE R. Khan et al, J Natl Med Assn,2001
Seizure like motor activity • Myoclonus • Nystagmoid eye movements • Eyelid fluttering • Conjugate eye deviations • Focal or multifocal twitching of the extremities R. Khan, J Natl Med Assn, 2001
Patients with “seizure like” motor activity • 10 – EEG slowing (nonspecific) • 1 - NCSE R. Khan, J. Natl Med Assn
HUP study • 152 patients to characterize specific events • Seizure incidence 31% • 363 patients with altered mental status • Seizure incidence 29%
Majority of movements in ICU are non-epileptic • Facial and eye twitching high correlate with seizure activity
52 cEEG studies for “possible seizures” • 14 (27%) had epileptic seizures • 38 (73%) had non-epileptic events • Tremor • Myoclonus • Slow semi-purposeful movements • Miscellaneous Benbadis, Epilepsia, 2010