Chromatin Insulators and Boundary Elements

Some of the organisational properties of the eukaryotic genome reside in the ability of chromatin to establish autonomous units that specify levels and patterns of gene expression.i.e. enhancers act on a promoter in a specific domain, but are unable to act on a promoter in a separate domain.The candidates charged with the function of establishing and delimiting domains of expression are boundary or insulator elements. These set up independent territories of gene activity.A few of these seque29923

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