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Human Genetics

Human Genetics . Monica Starbinski Greer Manton Sydney Gilbert Period 2 . Pedigrees. Key – -Male(affected) - Male (normal) -Female (affected) - Female (normal) - Heterozygous for recessive allele. Generation 1.

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Human Genetics

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  1. Human Genetics Monica Starbinski Greer Manton Sydney Gilbert Period 2

  2. Pedigrees Key – -Male(affected) - Male (normal) -Female (affected) - Female (normal) - Heterozygous for recessive allele Generation 1 Generation 2 Generation 3 • MonicaStarbinski

  3. Autosomal Recessive Disorders Albinism Phenotype ratio – 1 has disease : 3 do not Percentage – 25% have disease, 75% dont Genotype ratio – 1 AA : 2 Aa : 1 aa Percentage – 25% AA, 50% Aa , 25% aa The disorder is present. Cystic Fibrosis Tay-Sachs Disease

  4. Autosomal Dominant Disorders / Traits Phenotype ratio – 3 have disease : 1 does not Percentage – 75% have disease, 25% dont Genotype ratio – 1 GG : 2 Gg : 1 gg Percentage – 25% GG, 50% Gg, 25% gg The disorder is present. Free/Hanging Earlobes Huntington’s Disease Widow’s Peak Hairline

  5. Greer Manton Current Event on Human Genetics • http://www.sciencenews.org/view/generic/id/59938/title/Tracing_Jewish_roots

  6. Greer Manton Codominance Homozygous Genotype Ratio: 1 A1A1 : 2 A1A2 : 1 A2A2 Percentage: 25% A1A1, 50% A1A2, 25% A2A2 Phenotype Ratio: 1 Purple : 2 Red : 1 Yellow Percentage: 25% Purple, 50% Red, 25% Yellow Heterozygous R’ R RR’ Flower R RR’ RR Roan Cattle R’ R’R’ RR’

  7. Greer Manton Multiple Alleles Genotype Ratio: 1 TTWW : 3 TTWw, 2 TtWW : 4 TtWw, 2 Ttww : 1 ttWW, 2 ttWw : 1 ttww Percentage: 6.25% TTWW, 18.75% TTWw, 12.5% TtWW, 25% TtWw, 12.5% Ttww, 6.25% ttWW, 12.5% ttWw, 6.25% ttww HaemolyticAnaemia Dihybrid TtWw x TTWw

  8. Sydney Gilbert Sex-linked Disorders X Y Genotype Ratio: 1 XX; 1 XY; 1 XX’; 1 X’Y Phenotype Percentage: 25% XX; 25% XY; 25% XX’; 25% X’Y X X’ Hemophilia Color Blindness Down Syndrome

  9. Sydney Gilbert Questions! • 1: What is the chance that a mother can pass on the sex linked gene of color blindness? • 2: What is bound to happen when a pink flower is crossed with a white flower and results in codominance? • 3: If you are albino, what type of dominance do you have? • 4: If you possess attached earlobes, what type of dominance is it?

  10. Sydney Gilbert

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