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Liao F, Pascua J and The Madrid Acute Renal Failure Study Group, Kidney Int 1996; 50: 8111-818. Incidencia: 209/milln/ao (748/4.227.837)Etiologa: -NTA 45% -Prerrenal 21% -IRC agudizada 13% -Obstructiva 10% Origen: Extrahospitalario: 49
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1. Injuria renal agudaAspectos epidemiológicos Dr. Jordán Tenzi
9/7/07
2. Liaño F, Pascua J and The Madrid Acute Renal Failure Study Group, Kidney Int 1996; 50: 8111-818 Incidencia: 209/millón/año (748/4.227.837)
Etiología:
-NTA 45%
-Prerrenal 21%
-IRC agudizada 13%
-Obstructiva 10%
Origen:
Extrahospitalario: 49.7%
Hospitalario: 50.3%
-Medicina: 34%
-UCI: 27%
-Cirugía: 23%
Sexo: predominio masculino
Edad: incidencia aumenta con la misma
3. Liaño F, Pascua J and The Madrid Acute Renal Failure Study Group, Kidney Int 1996; 50: 8111-818 Mortalidad: 45%
NTA: 60%
Prerenal: 35%
IRC agudizada: 35%
Obstructiva: 27%
Nefritis intersiticial aguda: 13%
Vasculitis: 45%
Glomerulonefritis primaria: 9%
Glomerulonefritis secundaria: 25%
5. The epidemiology of acute renal failure: 1975 versus 2005
11. AKI incidence of 5% (109 of 2216 medical and surgical patients). AKI was associated with decreased renal perfusion (42%), major surgery (18%), radiocontrast exposure (12%), and aminoglycoside administration (7%). Predictors of poor prognosis included oliguria and the severity of the renal dysfunction.
14. Compared a cohort of 183 patients with radiocontrast-associated AKI and 174 patients who were matched for age and baseline SCr and underwent similar diagnostic procedures without developing AKI.
The mortality rate was 34% in patients with AKI versus 7% in patients without AKI. Adjusting for differences in comorbidity, the odds of death were increased 5.5-fold in the AKI group.
19. From this population, only patients who were treated with renal replacement therapy (RRT)
other than for drug poisoning or who had at least 1 of the predefined criteria for ARF were included in the study.
The criteria for ARF were oliguria defined
as urine output of less than 200 mL in 12 hours and/or marked azotemia defined as a blood urea nitrogen level higher than
84 mg/dL
29. Rialp G, Roglan A; Renal Failure 1996; 18: 667-675 Incidencia de IRA en UCI: 21.4%
AP: HTA 34.2% inmunodepresión: 27.3%
diabetes: 17.5%
Mortalidad: con IRA 46.6% p= 0.0001
sin IRA 17.6%
30. Injuria Renal Aguda en Medicina Intensiva Encuesta Multicéntrica NacionalJ Tenzi, A Ferreiro, R Lombardi, E Schwedt, N Nin, M Cancela, F Gonzalez y colaboradores
2006
31. Montevideo: 18 instituciones (25 UCI)
Interior: 15 instituciones (15 UCI)
Total UCI encuestadas: 40 (83%)
% UCI Montevideo encuestadas: 100%
% UCI Interior encuestadas: 65%
Incidencia de IRA: 9.12% (66/723)
37. Mortalidad pacientes con IRA: 32/66 (48.5%)
-Montevideo 23/53 (43.4%)
-Interior 9/13 (69.2%)
Mortalidad pacientes sin IRA: 107/657 (16.2%)
-Montevideo 88/518 (16.9%)
-Interior 19/139 (13.6%)
39. Sobreviven Fallecen Valor p
DOM
si 12 (35.3%) 22 (64.7%) < 0.05
DOM
No 21 (67.7%) 10 (32.3%)