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Chromosomal Disorders

Chromosomal Disorders. X Inactivation. Aneuploidy (incomplete sets). Trisomy Three copies of a chromosome 2n + 1. Aneuploidy (incomplete sets). Monosomy One copy of a chromosome 2n – 1. Polyploidy. More than 2 sets of chroms Triploid

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Chromosomal Disorders

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  1. Chromosomal Disorders

  2. X Inactivation

  3. Aneuploidy (incomplete sets) • Trisomy • Three copies of a chromosome • 2n + 1

  4. Aneuploidy (incomplete sets) • Monosomy • One copy of a chromosome • 2n – 1

  5. Polyploidy • More than 2 sets of chroms • Triploid • Diploid gamete (complete nondisjunction in meiosis) + haploid gamete • Tetraploid • Complete nondisjunction in mitosis

  6. Chromosomal Alterations

  7. Extranuclear Genes • Maternal Inheritance of DNA in plastids and mitochondria • Organelles are inherited maternally in plants and animals via the ovum (no paternal contribution)

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