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Capnography. Riding the wave of ventilation. “Technology, you can either embrace it or run from it…”. The Science. ETCO 2 Monitoring. Review of Pulmonary Anatomy & Physiology The primary function of the respiratory system is to exchange carbon dioxide for oxygen.
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Capnography Riding the wave of ventilation....
ETCO2 Monitoring Review of Pulmonary Anatomy & Physiology • The primary function of the respiratory system is to exchange carbon dioxide for oxygen. • During inspiration, air enters the upper airway via the nose where it is heated, humidified and filtered. • The inspired air flows through the trachea and bronchial tree to enter the pulmonary alveoli where the oxygen diffuses across the alveolar capillary membrane into the blood.
“CO2 is the smoke from the flames of metabolism.” - Ray Fowler MD
The unintentional and unrecognized esophageal intubation was identified as early as 1938 as a cause of mortality associated with anesthesia. The incidence was much lower than that of death from regurgitation/aspiration, which at the time was among the leading causes of perioperative death (Edwards 1938, Edwards et al, 1956, Maleck et al. 2001).
In 1979 a review of anaesthetic accidents forwarded to the Medical Defence Union of the United Kingdom between 1970 and 1977 found unrecognized esophageal intubation to be the most common cause of death and brain damage. The authors recommended NOT to rely on movements of the reservoir bag and the chest to identify the endotracheal tube (ETT) position and coined the well-known phrase "when indoubt, take it out" (Utting et al, 1979).
The capnogram has been described in text and picture as early as 1949. Both infrared (Luft, 1943; Fowler 1949) and mass spectrography devices (Kydd & Hitchcock, 1949) were already used at that time.
The application of capnometry for the detection of esophageal tube malposition was first proposed in 1981 and formally studied in 1983 (Ionescu, 1981; Kalenda & van der Vliest, 1982; Linko et al 1983; Murray & Modell, 1983; Klein & Moyes, 1984).
While by the mid 80's capnometry was rightly seen as the "gold standard" in checking the ETT position in hospital, this had little relevance for the out-of-hospital setting; no portable devices existed at that time. Also, at least in the English speaking countries which used (and use) paramedic based emergency medical systems, prehospital intubations were rare in the 1980s.
Definitions • Capnography: The measurement of Carbon Dioxide (CO2)in exhaled breath. • End Tidal CO2 (ETCO2 or PetCO2): The level of (partial pressure of) Carbon Dioxide released at end expiration.
ETCO2 detector types • Colorimetric: Positive color change in the presence of CO2. • Capnometer: The numeric measurement of CO2. • Capnogram: The expired wave form in addition to a numeric value.
The MiniCap III Gave an audible ‘beep’ in the presence of CO2
Colorimetric • pH sensitive, chemically impregnated paper encased in a plastic chamber that’s placed between the ETT and ventilation device • Color change is reversible • On the spontaneous breathing patient it will be purple on inhalation, yellow on exhalation
Pros Very accurate Inexpensive (~$10-15) Changes color when CO2 is present Continues to work up to two hours Disposable Cons Secretions Don’t detect hypo-or hypercarbia Increased deadspace Changes color when CO2 is present False positives Hard to read at night Colorimetric
Pros First generation of CO2 monitors Portable Given at least a numeric value Able to monitor a trend (?) Cheaper than capnography Cons Numeric value only Only found on eBay(?) Outdated Bulky adapter Treating the machine Capnometry
“End Tidal CO2 reading without a waveform is like a heart rate without an ECG recording.” - Bob Page
Pros Numeric value plus expiratory waveform Able to monitor a trend Ability to assess perfusion Very accurate Cons Expensive Fragile Warm-up time (?) Secretions Temperature sensitive (?) Capnography
Types of Technology • Infrared (IR) Spectroscopy • Side stream sampling • Main stream sampling • Microstream Technology
Infrared Spectroscopy • Technology most often used • Infrared light is used to expose the sample • Infrared sensors detect the absorbed light and calculate a value
Sidestream • “First generation” devices • Sample of exhaled gas is aspirated from the patients airway interface into the monitor which houses the sensor • Can be used in nonintubated patients • Secretions/moisture
Mainstream • “Second generation” • Sensor attaches directly to the airway • During exhalation, exhaled gas passes directly over the sensor • Primarily for intubated patients • Secretions • FRAGILE!
Microstream Technology • Samples 1/20th the volume • Vapor permeable tubing • Sub micron-multi-surface tubing • Expensive parts are protected • Microbeam IR sensor is CO2 specific • Can be used for adult and pediatrics
The Normal Capnogram • Phase I: Respiratory baseline • Phase II: Expiratory upstroke • Phase III: Expiratory plateau • ETCO2: Peak ETCO2 level • Phase IV: Inspiratory downstroke III II IV I
Hyperventilation • Narrow waveform • Decrease in CO2 • Hyperventilation syndrome • Overzealous bagging (CHI) • Pulmonary emboli • DKA
Hypoventilation • Narcotic overdose • CNS dysfunction • Heavy sedation
Before Narcan After Narcan
Apnea • Dislodged ET tube • Total obstruction of the ET tube • Respiratory arrest in the non-intubated patient • Equipment malfunction (if the patient is still breathing) check all connections and collecting chamber
Loss of Alveolar Plateau • Incomplete or obstructed exhalation • Asthma • COPD • Tube kinked or partially obstructed
on arrival after start of neb treatment after two A&A nebs
Elevated baseline • Air trapping (asthma or COPD) • CO2 rebreathing (ventilator circuit problem)
Poor perfusion (CPR) change • The capnogram can indicate perfusion during CPR and effectiveness of resuscitation efforts • The trough is when the rescuers switched • The fatigue of the first rescuer was demonstrated when the second rescuer took over compressions rescuer
Shocked ROSC ROSC ROSC ROSC
Field Applications for Capnography -Closed head injury -Obstructive pulmonary disease -Tube confirmation -Perfusion