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NCRN Quinquennial review

NCRN Quinquennial review. David Cameron. QQ Review. Who & By whom What Where When WHY? Where next…. QQ review – who?. Review of the Co-ordinating centre NOT OF THE NETWORKS Review party UKCRN lead DH CRUK NCRI Independents – External. QQ review – what?.

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NCRN Quinquennial review

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  1. NCRN Quinquennial review David Cameron

  2. QQ Review • Who & By whom • What • Where • When • WHY? • Where next….

  3. QQ review – who? • Review of the Co-ordinating centre • NOT OF THE NETWORKS • Review party • UKCRN lead • DH • CRUK • NCRI • Independents – External

  4. QQ review – what? • Submission of paperwork 15 Nov • Face-to-face on 21st January 2009 • Review of past performance • Review of processes/ principle • Discussion about future vision…

  5. QQ review – why? • Review of annual grant to fund CC • Are we (not you) value for money? • Review contribution of CC to Cancer research • Review of all TCRNs a few years in…

  6. QQ review – where next? • Report achievements to date • Define NCRN’s place in new universe • Redefine key relationships • Address challenges • Propose developments to continue to meet original aim “Improving the outcome for cancer patients by recruiting more patients to trials”

  7. Summary of past • Continued increase in accrual • Cancer RCTs dipped….starting to rise • Overall Cancer accrual up • Overall RCT accrual up • Evidence that not as many sites open in 2007/08 as in 2003/04 • EUCTD & other R&D/ research governance • Evidence of increasing follow-up burden Accrual ↑ whilst available trials and resource ….well done!!

  8. Initiatives • Follow-up burden • NCIN/NYCRIS post • Project officers – breast/lymphoma/urology • Funding • Re-distribution of underspend/ NRF • Pump-priming initiatives • Novel agents • Screening/ prevention studies • Data quality exercise

  9. Forward look • Screening/diagnosis/prevention trials • No central co-ordination • Individual trials may… • link to CSG • Ask for NCRN resource (& complain if they don’t get some..) • Recruit from very different parts of NHS • Portfolio of trials • Not necessarily strategically aligned • Now an NCRI and CRS priority…… • Clearly in the NCRN portfolio • Yet we are not solely responsible for accrual…

  10. Breakout sessions • 5 Clusters • CC staff and visitors (CRUK, NCRI) • Devolved nations • Can join a cluster • Can form their own cluster • Can hit the shops or gym……….. • Reactions to the following suggestions • Any other comments on current accrual

  11. Key questions for RNMs - 1 • Flexible funding • CC retains underspend and/or some of FSF • Redistribution exercise • Bidding system – all English networks • Targetted resources • Priority • NCRI or NIHR or loca • Fixed term – CLRN or commercial uptake • Hopefully 1-2 years’ funding How can you make this work in your network/ NHS host?

  12. Key questions for RNMs - 2 • Screening and Prevention • NOW IN THE CANCER PORTFOLIO • NCRN cannot supply all the resource • National and local engagement with • CLRN • PCRN • Research Funders • CC will have nominated lead for this area How will you do this locally?

  13. Key questions for RNMs - 3 • Geographical alignment • Cancer networks • Patient journeys • Clinical links • NSSGs and MDTs • Comprehensive networks • Source of service support cost • NCRN income generating for CLRNs How to have two partners?

  14. Key questions for RNMs - 4 • Initiatives • NCRI • Supac, lung cancer, prostate cancer • Screening/ prevention trials • NIHR • Commercial trials • More RCTs • Complete studies on time How can you make your network respond to initiatives?

  15. Key questions for RNMs - 5 • Networking • Inter-hospital referrals for studies • Inter-network referrals for studies • Overcoming perceived NHS barriers • Encourage knowledge of full portfolio • Commercial trials and non-commercial • Across the network • In adjacent networks What can you do to enhance accrual by better networking?

  16. Key questions for RNMs - 6 • Data quality • Accruing patients is not enough • Accurate data needed • No clear definition • Timeliness, accuracy, completeness • Sponsor/ site responsibility • BUT……NCRN needs to know that our data is good! • Round-robin approach • Site visits with CTU staff + NCRN staff from another network What problems and benefits can you see from this?

  17. Questions not for QQ • End sept meeting with NHS chief execs…… • How do we encourage the NHS to support research • Consultants • Nurses • CNS, out-patient and in-patient staff • Service departments • Path/radiology/pharmacy • HR / Finance etc.

  18. Vision • NCRN CC here to support the networks & funders • Continue the good work you have already done • Remain at the forefront of world cancer trial accrual • Drive the engagement with the new NHS research world…..be patient! • Embed research in the NHS • Work collectively not individually • NCRI • CRUK & other funders • CLRN • PCRN & other TCRNs

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