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So, Doctor, what is LHON?

So, Doctor, what is LHON?. LHON is a disease of the mitochondria. mitochondria. Those are the things in cells that supply energy. They're in the cytoplasm, yes?. That's right! Now what do you know about genes ?.

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So, Doctor, what is LHON?

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  1. So, Doctor,what isLHON? LHON is a disease of the mitochondria. mitochondria.Those are the things in cells that supply energy. They're in thecytoplasm, yes? That's right! Now what do you know about genes?

  2. Genes control a lot of your features – like your eye colour. You get them from your dad’s sperm cell and your mum’s egg cell. Well done! What normally happens when a sperm fertilises an egg?

  3. Thesperm nucleusgets into theegg. Then the egg nucleus and sperm nucleus join together to make your first complete cell. Exactly! But whose mitochondria did you get?

  4. All your mitochondria come from your mum. You only get a nucleus from your dad. That's right! But mitochondria have a few genes in them, and Maya's are faulty. That's why she went blind. So her children will go blind too? Yes. And I am afraid there's no treatment. But scientists are working on it. Let me explain.

  5. Right, Darcy. I'll let you get back to your patients. You'll have to tell Maya and Jake that there is no solution to their problem. There might be a treatment in future, but will it be too late? n How 2-parent fertilisation usually happens n The scientists' idea for 3-parent fertilisation n Why and how 3-parent fertilisation might help them in future…if they can wait. Plan what to say to Maya and Jake. Prepare diagrams to help you explain:

  6. Can I ask you something else? I'm thinking of become a nurse or health care assistant. Can you tell me about your work? My job is not easy. I have to tell people difficult things. I need to be emotionally strong and physically fit. I have to stay calm in a crisis. But I love my work. It's really rewarding. And there's no chance to get bored! So what skills do health care assistants and nurses need?

  7. What about qualifications? Health Care Assistantssupport other health professionals in hospitals or homes. You do not need academic qualifications, but experience in a caring role is helpful (try doing volunteer work with your local NHS Trust). Most health care assistants work towards NVQ levels 2 or 3 in 'health' or 'health and social care'. With NVQ Level 3 you could start a university-based nursing diploma. Here – take a look at this leaflet. Nurses with diplomas or degrees n With 5 A-C grades at GCSE (including English) at aged 17½ you could begin a 3 year diploma course at university to train to be a nurse. You get a bursary of about £100 per week and all your fees are paid. n With A Levels, including at least one in a relevant science, you could begin a 4-year degree course.

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