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Chapter 15 – The Chromosomal Basis of Inheritance

Chapter 15 – The Chromosomal Basis of Inheritance. Sex Determination. Sex-linked genes. Sex linked inheritance. Must show sex chromosomes Hemizygous. X inactivation. Barr body. Linked genes. Nondisjunction. Aneuploidy Monosomy Trisomy. Down syndrome. Trisomies in sex chromosomes.

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Chapter 15 – The Chromosomal Basis of Inheritance

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  1. Chapter 15 – The Chromosomal Basis of Inheritance

  2. Sex Determination

  3. Sex-linked genes

  4. Sex linked inheritance • Must show sex chromosomes • Hemizygous

  5. X inactivation • Barr body

  6. Linked genes

  7. Nondisjunction • Aneuploidy • Monosomy • Trisomy

  8. Down syndrome

  9. Trisomies in sex chromosomes • Klinefelter syndrome 47, XXY • Jacob syndrome 47, XYY • TriploX 47, XXX

  10. Monosomy in sex chromosome • Turner syndrome 45, XO

  11. Chromosome structural abnormalities • Deletion • Duplication

  12. Chromosome structural abnormalities cont • Inversion • Translocation

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