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Trends in cancer Incidence in the Republic of Mauritius, 1991-2015. MARVIN KOON SUN PAT. Background. Population Different ethnicities : India, East Africa, China, Europe Upper middle income country with a GDP per capita of 9469.90 US dollars
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Trends in cancer Incidence in the Republic of Mauritius, 1991-2015 MARVIN KOON SUN PAT
Background Population Different ethnicities : India, East Africa, China, Europe Upper middle income country with a GDP per capita of 9469.90 US dollars Cancer care facilities: one radiotherapy department and a centralised pathology service. Chemotherapy is decentralised to the five regional hospitals over the island
The Mauritian National Cancer Registry • Established in 1993 by Dr S. MANRAJ • Data on Cancer Incidence has been collected on a continuous basis from 1989 • Affiliation to the IACR in 1997 • Population based in 2000 • Hosted the 33rd annual meeting of IACR in October 2011 • Affiliation to the AFCRN in 2014
Objectives • Trends in cancer incidence in the small state country for twenty five years (1991-2015) • Quality indicators of the registry (2006-2015) • Age unknown • Primary sites unknown • Percentage of cases with a morphologically verified diagnosis • Mortality to incidence ratio the mortality to incidence ratio (MIR)
Materials and Methods • All cancer patients registered in the Republic of Mauritius from 1st January 1991 to 31st December 2015 MNCR CIVIL STATUS OFFICE PRIVATE PATHOLOGISTS RADIOTHERAPY UNIT PATIENT REGISTER OVERSEAS TREATMENT UNIT HOSPITAL HEALTH RECORDS LABORATORY ARCHIVES
Results • 36 901 observations (¼ males and ¾ females ) • Males • ASR = 95 per 105 (1991-1995) to 133 per 105 (2011-2015) • AAPC = 1.4% (95% CI: 0.8 to 2.0) • Females • ASR = 116 per 105 (1991-1995) to 151 per 105 (2011-2015) • AAPC = 1.4% (95% CI: -0.6 to 2.2)
TRENDS IN incidence rate in FIVE MOST FREQUENT CANCER AMONG FEMALES AAPC +3,4%* +4.4%* -3.6%* 5.2% -0.1%
TRENDS IN INCIDENCE RATE IN FIVE MOST FREQUENT CANCER AMONG MALES AAPC +3.9%* +4.2%* +0.5% -0.1% -1.3%*
Pediatric Tumors • Children (0 to 14 years) • 803 cases, 57% occurred in males and 43% in females • Leukemia= 34% • Mean age 6 years old • Brain-nervous-system = 11% • Mean age 7 years old
In Summary • Cancers related to the “westernisation” of lifestyle • The most common sites and feature the most dramatic increase • Contrast with other Sub-Saharan African countries • HIV and other infection related cancers are most predominant • Prevention by stronger public health action • Tobacco and alcohol control, immunisation and better nutrition and weight control
Next Steps • Accreditation for MNCR in the next CI5 manual • Introduction of survival studies • Submission for publication – peer reviewed • Conversion of MPhil to PhD degree
THANK YOU • Co-authors: • DrMANRAJ Meera • DrFAUZEE Jasmine • DrSEWSURN Sashi • DrPARKIN Maxwell Donald • DrMANRAJ Shyam • Financial support Tertiary Education Commission of Mauritius