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Jelly electrophoresis: a new method of sandwich analysis. Gregory J. Crowther, Ph.D. U.W. Department of Chemical Engineering. Gel electrophoresis. Purpose: separate molecules of different sizes. molecules pass through a gel small molecules travel faster than large ones
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Jelly electrophoresis:a new method of sandwich analysis Gregory J. Crowther, Ph.D. U.W. Department of Chemical Engineering
Gel electrophoresis Purpose: separate molecules of different sizes • molecules pass through a gel • small molecules travel faster than large ones • drawback: gel is not edible
Bread is like gel, but more appetizing • solid yet porous • molecules pass through it • speed reflects size
How big is a jelly molecule? Goal: determine size of a jelly molecule from its migration through a slice of bread. Other items tested: water, turkey, cheese* migration direction
10-18 10-19 10-20 10-21 10-22 10-23 jelly Molecule size (grams) 0 1 2 3 Distance traveled (centimeters) Results • One jelly molecule is 0.00000000000000000015 grams • Equivalent to 0.0000000000000000006 calories
Conclusions • Jelly molecules are surprisingly large. • Nevertheless, they do migrate through bread. • Therefore, jelly sandwiches should be eaten soon after being made to prevent the jelly from escaping.
Sourdough Pumpernickel Whole wheat Rye Future work
Acknowledgments • M. Lambeth, D. Marcinek, E. Shankland, and R. Stuppard contributed and/or consumed materials used in this study. • This research was supported by a grant from the J.M. Smucker Company.