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The architecture of the PTP1B active site. Phosphotyrosine (Substrate). Phe180. Gln262. Q-loop. pTyr-loop. Tyr46. Asp181. WPD-loop. PTP-loop. Arg221. Cys215. http://ptp.cshl.edu or http://science.novonordisk.com/ptp. Courtesy of Dr. Robert Del. Vecchio.
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The architecture of the PTP1B active site Phosphotyrosine (Substrate) Phe180 Gln262 Q-loop pTyr-loop Tyr46 Asp181 WPD-loop PTP-loop Arg221 Cys215 http://ptp.cshl.edu or http://science.novonordisk.com/ptp Courtesy of Dr. Robert Del. Vecchio