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Bioinformatics : Science that derives information from computer analysis of biological data

Bioinformatics : Science that derives information from computer analysis of biological data. Information flow:. Input. Storage. Retrieval. Data analysis. Concepts of computational science, statistics, mathematics, linguistics, biological sciences. Hypothesis. Inductive process.

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Bioinformatics : Science that derives information from computer analysis of biological data

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  1. Bioinformatics: Science that derives information from computer analysis of biological data Information flow: Input Storage Retrieval Data analysis Concepts of computational science, statistics, mathematics, linguistics, biological sciences... Hypothesis Inductive process Deductive process Data Bioinformatics refers to the creation and advancement of algorithms, computational and statistical techniques, and theory to solve formal and practical problems posed by or inspired from the management and analysis of biological data. Computational biology refers to hypothesis-driven investigation of a specific biological problem using computers, carried out with experimental and simulated data, with the primary goal of discovery and the advancement of biological knowledge Data: 1) Information from genomes / genetic code 2) Biochemical results, patient statistics, etc. 3) Scientific literature

  2. Diego Sánchez Instituto de Biologia y Genética Molecular Universidad de Valladolid-CSIC C/Sanz y Forés s/n 47003 Valladolid Tfno: 983-184814 Fax: 983-184800 E-mail: lazarill@ibgm.uva.es

  3. Databases (raw and curated-annotated data) Sequence and structure databases (DNA and proteins): General DB: GenBank, Protein structure (PDB), SwissProt, ESTdb, SNPs… Genome DB: Human Genome; Mouse… Organism-specific: Flybase; ACEDB; Zebrafish… Relational DB: HomoloGene; CDD; Prosite... Scientific literature: Pubmed, Medline Zoology: Taxonomy, Tree of life Global and relational DB: Entrez; Ensembl; GOdb… Web-based analysis platforms NCBI; ExPASy; EBI…

  4. fFGF rFGF2 rFGF2 chFGF2 chFGF2 rFGF7 rFGF7 chFGF7 chFGF7 rFGF2 and chFGF2 are orthologs rFGF2 and rFGF7 are paralogs Time fFGF and chFGF7 are homologs 75 My 350 My Genes-proteins relationships: Orthology, homology, paralogy, analogy and xenology

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