NUR 316 Management of the Diseases in the Respiratory S ystem

1. NUR 316Management of the Diseases in the Respiratory System

2. Learning objectives At the end of this modules, students will be able: • Describe the structures and functions of the upper and the lower respiratory tracts. • Discriminate between normal and abnormal assessment findings identified by inspection, palpation, percussion, and auscultation of the respiratory system. • Recognize and evaluate the major symptoms of respiratory dysfunction. • Identify the diagnostic tests to evaluate respiratory function.

3. Glossary • Apnea: temporary cessation of breathing. • Bronchoscopy: direct examination of the larynx, trachea, and bronchi using an endoscope. • Dyspnea: difficulty/ shortness of breath. • Hypoxemia: decrease in arterial oxygen tension in the blood. • Hypoxia: decrease in oxygen supply to the tissue and cells. • Hemoptysis: expectoration of blood from the respiratory tract. • Orthopnea: inability to breathe easily except in an upright position. • Tachypnea: abnormal rapid respiration.

4. Anatomy and physiologic • Respiratory system is responsible for ventilation (movement of air in and out of the airways). • It composes of upper and lower respiratory tracts. • Upper airway warm and filter the inspired air.

5. Anatomy and physiologic(cont.) • Gas exchange: delivering oxygen to the tissue through the blood steam (inspiration) and expelling waste gases, such as carbon dioxide, (expiration).

6. Anatomy and physiologic(cont.) Ventilation is effected by three factors: • Airway pressure: the movement of the diagram during inspiration create a negative pressure which permits ventilation. • Airway resistance: determined by the size/radius of airways. • Compliance: is the elasticity and expandability of lung and the thoracic cavity. Requires the presence of the “surfactant”.

7. Anatomy and physiologic(cont.) • Pleural: • Covers the lungs. • Has two layers and fluid to lubricate the lungs and thoracic cavity.

8. I-Health history • Elicit a description of the present illness and chief complaint, including onset, course, duration, location, and precipitating and alleviating factors. Cardinal signs and symptoms of respiratory dysfunction include:- • Dyspnea • Orthopnea • Cough which may be productive or non productive • Increased sputum, which may be purulent (yellow or green),rusty, bloody, or mucoid sputum • Chest pain • Wheezing and crackles • Clubhing of fingers • Hemoptysis • Cyanosis (e.g. buccal, peripheral)

9. - b-Explore the client's health history for risk factors associated with respiratory disease including : • (1) Personal or family history of lung disease • (2) Smoking (the most significant contributing factor in lung disease) • (3) Occupational or vocational exposure to allergens or environmental pollutants • ( 4) Age-related changes in lung capacity and respiratory function • (5) History of upper respiratory infection • (6) Postoperative changes resulting in diminished respiratory excursion

10. Physical examination • a- Inspection • (1) observe general appearance, noting body size, age, skin quality and color, and posture. • (2) Inspect configuration and movement of the thorax during respiration. • (3)Assess characteristics of respiration, including rate, rhythm, depth and muscles used for breathing. • (4) Note presence of cough and the nature and character of sputum (e.g. purulent, bloody)

11. Palpation. Palpate the chest to detect painful areas or masses on the chest surface and evaluate chest excursion and the presence or absence of fremitus (i.e. vibration). • Percussion. Assess chest sounds to evaluate underlying tissues. Resonant sound indicates air-filled lung (normal), whereas dull or flat sound suggests presence of firm mass (usually abnormal). Hyperresonant sound in emphysema.

12. Auscultation. Listen to air movement in lungs to detect normal or adventitious breath sounds. • (1) Vesicular sounds are low-pitched, rustling sounds heard over most of lung field, most prominently on inspiration. They indicate normal, clear lungs. • (2) Bronchial sounds are high-pitched tubular sounds with a slight pause between inspiration and expiration. They are normal over large airways. • (3) Bronchovesicular sounds are combination of vesicular and bronchial sounds, normally heard anterior to the right or left of the sternum and posterior between the scapulae; inspiration and expiration are equal. ' • (4) Adventitious breath sounds are crackles (i.e. fine to coarse), wheezes and pleural friction rub. https://www.youtube.com/watch?v=5JA6D1Mguh0

13. Laboratory and diagnostic studies • Radiographic and scanning studies are done to visualize respiratory system structures. The studies include: • Chest radiography, • chest tomography • Lung scan • Computed tomography (CT) scan • Magnetic Resonance Imaging(MRI).

14. Bronchoscopy studiesare invasive techniques performed to visualize pulmonary structures and obtain tissue specimens.

15. used to examine thoracic structureThoracoscopy:

16. Thoracentesisinvolves needle aspiration of pleural fluid for diagnostic and therapeutic purposes.

17. Needle biopsy is an invasive technique that involves entering the lung or pleura to obtain tissue for analysis. • Pulmonary function test(PFT): it is done to measure functional ability of the lung through measuring lung volumes and capacities. • Sputum culture determines the presence of pathogenic organisms. • Arterial blood gas (ABG) studies determine O2 and CO2 content and evaluate the body's acid-base balance • Pulse Oximetry: Monitoring oxygen saturation of hemoglobin (SpO2 or SaO2). • Incentive spirometer: provide visual feedback to encourage the patient to maximize lung inflation and prevent atelectasis.

18. Nursing diagnosis • Ineffective breathing pattern • Impaired gas exchange • Altered tissue perfusion (peripheral) • Activity intolerance • Pain • Anxiety • Ineffective individual coping • Knowledge deficit • Risk for infection

19. Implementation • Assess respiratory status and tissue perfusion, including respiratory rate, depth and effort; level of consciousness; lung sounds; peripheral cyanosis; cap­illary refill time; color and consistency or sputum; and pulse oximetry. • Improve breathing patterns. a. Encourage upright position (semi-Fowler or high-Fowler position) b. Encourage the client to increase fluid intake to at least 2 to 3 liters of fluid each day, unless contraindicated as in congestive heart failure. c. Use of incentive spirometer

20. Promote gas exchange • Administering oxygen therapy. • Analyze ABG values and pulse oximetry to determine need for oxygen therapy. • Assist in administering nebulizer treatment. • Encourage effective coughing. Instruct client to take three deep breaths in through the nose and out through the mouth, and on the third breath pull in the abdominal muscles and cough twice forcefully with mouth open. • Encourage the client to lie on the affected side to splint the area if there is pain when coughing. • Encourage the client to eliminate or minimize exposure to all pulmonary irritants, and advise the client to quit smoking.

21. Improve activity tolerance. Encourage client to alternate rest with activity to prevent overexertion that may exacerbate symptoms and to increase activity gradually. • Provide pain management. • Assess the client for pain, and exclude other potential complications. • Instruct the client about splinting when the client has chest pain, • Promote infection control measures. • Instruct the client to avoid crowds or people with known colds, flu, or respiratory infection. • b. Implement standard precautions and droplet or airborne precautions as indicated.

22. Upper respiratory Tract Infection(URTI) URTI follows invasion of the upper respiratory organs by microbes. • Upper respiratory organs include the: Nose, sinuses, throat • Common cold is an example of an upper respiratory infection. • Common cold is caused by a virus • Symptoms:- Elevated temperature (fever) • Runny nose • Watery eyes Treatment of common cold: • Use of antipyretic such as aspirin • Rest • Increased fluid intake • Upper respiratory infections sometimes move down into the chest and develop into bronchitis or even pneumonia.

23. Pneumonia • Description. Pneumonia is an inflammatory process involving the respiratory bronchioles, alveolar space and walls, and lobes, caused primarily by chemical irritants or by specific bacterial, viral, fungal, mycoplasmal, or parasitic organisms. • Pneumonia is the most common cause of death from infectious disease in North America and the fifth leading cause of death among the elderly.

24. Types of pneumonia: • Community Acquire Pneumonia: (CAP) occurs either in the community setting or within the first 48 hours of hospitalization. The organisms that most frequently cause CAP are Streptococcus pneumonia, Haemophilus influenza, and atypical organisms ( Legionella, Mycoplasma, Chlamydia& viral) • Hospital Acquire Pneumonia :(HAP) also known as Nasocomial infection Occurring 48 hours or longer after admission to the hospital. Bacteria are responsible for the majority of HAP infection, including Pseudomonas and Enterobacter, Staphylococcs aureus and Streptococcus pneumonia.

25. Pneumonia in Immunocompromized Host: E.g. pneumocystic carinii , fungal & tuberculosis. It is occur most commonly in patient with AIDS , nutritional depletion , use of broad –spectrum antimicrobial agent, corticosteroids, chemotherapy, and long term life- support technology (mechanical ventilation) • Aspiration Pneumonia: refers to entry of endogenous or exogenous substance into the lower air way such as gastric content.

26. Causes of and contributing 1- Smoking and air pollution 3- Altered consciousness: alcohalizm, head injury, seizure, anaesthesia, drug overdose 4- Tracheal intubations (endotracheal intubations, trachestomy) 5- Upper respiratory tract infection 6- Chronic diseases: chronic lung disease, diabetes mellitus, heart disease, uremia, cancer, 7- Immunosuppressant 8- Malnutrition 9- Inhalation or aspiration of noxious substances 10- Bed rest and prolonged immobility 11- Depress cough reflex

27. Pathophysiology. • Pneumonia often affects both ventilation and diffusion . An inflammatory reaction occurs in the alveoli, producing an exudates that interferes with the diffusion of oxygen and carbon dioxide and fill the alveolar air spaces, producing lung consolidation • Areas of the lung are not adequately ventilated because of secretions and mucosal edema that cause partial occulsion of the bronchi or alveoli with a resultant decrease in alvelor oxygen tension and bronchospasm may occur. • Ventilation – perfusion mismatching or Impaired gas exchange in the alveoli leads to various degrees of hypoxia, depending on the amount of lung tissue affected.

28. Clinical manifestations • A- Typical pneumonia syndrome is characterized by: • Sudden onset fever over 40 C , chills, cough productive with Purulent sputum and pleurisy chest pain, dullness with consolidation on percussion of chest ,dyspnea, respiratory grunting, and nasal flaring ,Flushed cheeks; cyanotic lips and nail beds ,anxiety and confusion. In the elderly, the only signs may be mental status change and dehydration. • B- Atypical Pneumonia syndrome: is characterized by gradual onset, dry cough and extrapulmonary manifestations as headach, fatigue, sore throat, nausea, vomiting and diarrhea. Crackles are heard.

29. Laboratory and diagnostic study findings • Chest radiograph shows density changes, primarily in the lower lung fields. • Sputum culture and sensitivity are positive for a specific causative organism. • While blood cell (WBC) count is elevated in pneumonia of bacterial origin; WBC count is depressed or normal in pneumonia of mycoplasma or viral origin.

30. Nursing management • Administer prescribed medications, which may include: • Antibiotics (Penicillne, Erthromycine, Gentamicine) • Mucolytics. expectorants, or antitussive agents& antipyretic • Promote infection control measures, especially droplet precautions as indicated. • Prevent aspiration pneumonia in a client receiving tube feedings. Keep the client in an upright position during feedings and for 30 minutes afterward. Check for residual gastric contents; if more than 100 mL, stop feeding and reevaluate. • Oxygen administer • Warm, moist inhalation • Increase fluid intake

31. Complication of pneumonia: • 1- Pleurisy: inflammation of pleura • 2- Pleural effusion: accumulation of fluid in pleural space • 3- Empyema: accumulation of pus in pleural space • 4- Atelectasis: collapsed, airless alveoli of one or part of one lobe may ocurr • 5- Pericarditis: inflammation of pericardium • 6- Arthritis: inflammation of joint • 7- Meningitis: inflammation of brain layer • 8- Lung abscess

32. Chronic obstructive pulmonary disease • Chronic obstructive pulmonary disease (COPD) is a group of disorders associated with persistent or recurrent obstruction of air flow, which include chronic bronchitis, emphysema, and asthma. • These conditions frequently overlap. • Most commonly, bronchitis and emphysema occur together. • Asthma frequently occurs alone without the triad of bronchitis, emphysema, and asthma.

33. Etiology • 1-Chronic bronchitis and emphysema. Major causes and contributing factors to these disorders, which are irreversible, include • Smoking • Air pollution • Occupational exposure to respiratory irritants • Allergies • Autoimmunity • Infection • Genetic predisposition • Aging

34. 2- Asthma is a reversible diffuse airway obstruction with a possible genetic component. It may be extrinsic or intrinsic. • Extrinsic factors include external agents or specific allergens (e.g. dust, foods, mold spores, insecticides). • Intrinsic factors include upper respiratory infection, exercise, emotional stress, cold, or other nonspecific factors. • Status asthmatics is a severe and persistent asthma that lasts longer than24hours and does not respond to conventional therapy.

35. Pathophysiology. COPD disrupts airway dynamics, resulting in obstruction of airflow into or out of the lungs. • Chronic bronchitis. Hypertrophy and hypersecretion in goblet cells and bronchial mucus glands leading to increased sputum secretion, bronchial congestion, narrowing of bronchioles, and small bronchi.

36. Emphysema. Increased size of air spaces (i.e. dead space) with loss of elastic recoil of lung due to hyperinflation of distal airways causes airway obstruction. Destruction of alveolar walls and diffuse airway narrowing causing resistance to airflow because of loss of supporting structure bronchospasm further impede airflow.

37. Asthma. Basic pathologic changes include: • Narrowing of the bronchial airways • Bronchospasms • Increased mucosa • Mucosal edema secondary to inflammation.

38. Clinical manifestations • Chronic bronchitis (1) History of productive cough that lasts 3 months per year for 2 consecutive years (2) Persistent cough, known as smoker's cough, usually in the winter months (3) Persistent sputum production (4) Recurrent acute respiratory infections (5) "Pink puffer appearance

39. Emphysema (1) History of chronic bronchitis (2) Slow onset of symptoms (typically over several years), which can lead to right sided heart failure (i.e. cor pulmonale) (3) Progressive dyspnea, initially only on exertion and later also at rest (4) Progressive cough and increased sputum production, use of accessory muscles (5) Anorexia with weight loss and profound weakness (6) Dusky color leading to cyanosis (7) Clubbing of fingers

40. Asthma (1) Chest tightness and dyspnea (2) Cough (3) Wheezing (4) Expiration more strenuous and prolonged than inspiration (5) Use of accessory muscles of respiration & nasal flaring (6) Hypoxia with restlessness, anxiety, cyanosis, weak pulse, and diaphoresis

41. Laboratory and diagnostic study findings • Chronic bronchitis (1) Pulmonary function studies identify decreased forced expiratory volume (FEV), decreased forced vital capacity (FVC), increased residual volume (RV), and total lung capacity (TLC) that is normal to slightly increased. (2) Chest radiograph shows an enlarged heart with a normal or flattened diaphragm. (3) ABG studies during the acute phase show significantly increased Paco2 and decreased Pa02. (4) Sputum culture reveals secondary bacterial infection with gram-negative or gram-positive organisms, such as Diplococcuspneumoniaeand H.influenzae.

42. b. Emphysema (1) Pulmonary function studies identify decreased FEV, decreased FVC, increased RV, and increased TLC. (2) Chest radiograph shows a Flattened diaphragm, decreased vascular markings with hyperradiolucence, and increased anteroposterior (AP) diameter (i.e. "barrel chest"). (3) ABG studies detect increased PaC02 and decreased Pa02 (4) Blood analysis reveals polycythemia (i.e. increased numbers of red blood cells in response to hypoxemia). • C.Asthma. (1)-Pulmonary function studies during acute episode identify markedly decreased FEV, increased RV, and increased TLC in response to air trapping. These study values improve after treatment.

43. Nursing management • Provide nursing care for the client with chronic bronchitis or emphysema. • a. Administer prescribed medications, which may include antibiotics, bronchodilator, mucolytic agents, and corticosteroids. • Antibiotics should be administered at the first sign of infection, such as a change in the sputum. • Narcotics, sedatives, and tranquilizers, which can further depress respirations, should be avoided.

44. Clear airways with postural drainage, percussion (i.e. clapping) or vibrating, and suctioning as appropriate

45. Promote infection control. Encourage the client to obtain influenza and pneumonia vaccines at prescribed times. • Improve breathing patterns. Demonstrate and encourage diaphragmatic and purse-lip breathing. Have the client take a deep breath and blow out against closed lips.

46. Provide nursing care for the client with asthma • Administer prescribed medications, which may include: • Adrenergics( Adrenaline), • Bronchodilators(aminophlline) • Corticosteroids( Dexamethasone, Solu –cortef) for acute attack . • Nebulized aerosol(Ventoline) relive bronchospasme. • Oxygen therapy

47. Provide treatment during an acute asthmatic attack. • (1) Stay with the client and keep him calm and in an upright position. • (2) Do purse-lip breathing with the client; encourage relaxation techniques.

48. Implement measures to prevent asthmatic attacks. Teach the client the following skills: (1) Identify and eliminate or minimize exposure to pulmonary irritants. (2) Remove rugs and curtains from the home; change air filters frequently; keep the home as dust free as possible; and keep windows closed during windy and high pollen days. (3) Use an inhaler and take medications as prescribed, and notify the physician when not gaining complete relief. (4) Notify the physician when a respiratory infection occurs. (5) Obtain influenza and pneumonia vaccines at prescribed times. (6) Monitor peak expiratory flow rate.

49. Pleural effusion • Description. Pleural effusion is a collection of fluid in the pleural space, which is located between the visceral and parietal surfaces • Etiology. Pleural effusion usually results from diseases such as neoplastic tumors (of which bronchogenic cancer is the most common malignancy), congestive heart failure, tuberculosis, pneumonia, pulmonary infection, and connective tissue disease. • Pathophysiology. The pleural space contains a small amount of lubricating fluid that allows the pleural surfaces to move without friction. Excess fluid accumulates in the space until it becomes clinically evident. The effusion can be composed of a clear fluid, or it can be bloody or purulent.

50. Clinical manifestations • Large pleural effusion (1) Shortness of breath (2) Minimal or no breath sounds (3) Dull, flat sound when percussed (4) Tracheal deviation away from the affected side may occur when significant accumulation of fluid occurs. • Small to moderate pleural effusion (1) Respiratory difficulty or comprised lung expansion may not be evident. (2) Dyspnea may not be present.