1 / 8

Flow measurements in up-scaled bifurcation models using MRI

Explore how MRI combined with dynamic scaling techniques accurately measures coronary artery flow, validating computational flow modeling in cardiovascular studies.

markhunter
Download Presentation

Flow measurements in up-scaled bifurcation models using MRI

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Flow measurements in up-scaled bifurcation models using MRI Susann Beier John Ormiston, Mark Webster, Brett Cowan,Pau Medrano-Graciaand Alistair Young

  2. Background • MRI is the state-of-the-art for measuring vascular flow but is limited in coronaries • Computer flow modelling is preferred but must be validated • MRI spatial limitations can be overcome with up-scaled phantom flow acquisition Computational flow modelling Experimental flow modelling

  3. Background • Law of Dynamic Similarity describes IDENTICAL flow systems on different prototype scales • Commonly used in Engineering, e.g. Aeroplane design • Scaling in vitro flow and phantom reproduces accurate coronary artery flow Law of Dynamic Similarity

  4. Methods Large phantom 4D flow MRI • CTA vessel geometry was virtually up-scaled and 3D printed • Phantom was incorporated into a non-Newtonian fluid flow circuit • Phantom flow was measured with MRI Non-Newtonian fluid

  5. Results Idealised Stented Patient-specific CFD • Tested various geometries • CFD and MRI agreed well in velocity magnitude • CFD and MRI agreed also well velocity direction MRI r2=0.87 r2=0.88 r2=0.91

  6. Results diff Patient-specific geometry CFD MRI • Complex flow features were captured in whole 3D volume

  7. Conclusions • Dynamically scaled in vitro MRI flow can accurately assess coronary flow • Stent induced flow alterations can be measured • Validates CFD and may provide boundary conditions

  8. Acknowledgements Co-investigators John Ormiston, Mark Webster, Alistair Young, Pau Medrano-Gracia, and Brett Cowan Funding Auckland Heart Group Charitable Trust

More Related