המינהלת הישראלית למו"פ האירופי The Israel-Europe R&D Directorate

Ministry of Science Technology & Space המינהלת הישראלית למו"פ האירופי The Israel-Europe R&D Directorate Nano-Materials-Biotechnology & Research Infrastruc.H2020 first calls (2014-2015) Dr. Nili Mandelblit, ISERD Director of Space, Transport, Nano-Materials-Production-Biotechnology, RI Weizmann Institute 12 January 2014

ISERD Steering Committee: Ministry ofEconomy Ministry of Science, Technology & Space Ministry of Foreign Affairs Ministry of Finance the Council for Higher Education – Planning and Budgeting Committee Chairman of the Steering Committee: Mr. Avi HASSON, Chief Scientist, Ministry of Economy General Manager: Mr. Marcel SHATON

Support Programs Along the R&D Chain Risk Basic Research PBC (Vatat) & ISF Ministry of Science, Technology & Space Other Ministries OCS Ministry of Economy Applies Academic Research International Program EU FP Support Policy Research Nofar Bilateral EUREKA Tnufa Incubators MAGNET Magnet Competitive R&D Market Proximity

What is the European Framework Program (FP)? • EU's main funding instrument for R&D (since 1984) • Covering almost all scientific/tech. disciplines • Goals: • Strengthen the scientific & technological base of European industry (“Increase competitiveness”) • Create a “European Research Area” (ERA) • Promote research that supports EU policies • Funding implemented via calls for proposals, each covering specific research areas

The EU Framework Program FP 7

The EUFramework Program (FP) EU Member State (28) FP7 Associated States (12)

Israel is an Associated State that allows it full participation in the Framework RTD Programs since 1996 (mid FP4)

H2020 - The next EU FP (2014-2020) • A 70.2Billion Euro Research and Innovation funding program • Goals: • Responding to the economic crisis to invest in future jobs and growth • Addressing people's concerns about their livelihood, safety and environment • Strengthening the EU's global position in research, innovation and technology • Focus on societal challenges facing EU society (e.g. health, transport, energy efficiency, …) • Calls for proposal published on December 11, 2013

H2020 - Three Pillars: • Excellent Science (€24.5 Billion) • Industrial leadership (€17.9 Billion) • Societal Challenges (€30 Billion)

EXCELLENT SCIENCE-24.5 € B SOCIETAL CHALLENGES-30€ B European Research Council-ERC -13 268M€ Frontier research by the best individual teams Food-4152M€ security, sustainable agriculture, marine and maritime research & the bioeconomy Nanotechnologies Future and Emerging Technologies-3100M€ Collaborative research to open new fields of innovation Marie Curie - 5752M€ Opportunities for training and career development Research Infrastructures 2478M€ Ensuring access to world-class facilities Homeland Security Innovative societies 3 Challenges (70.2 B Euros) INDUSTRIAL LEADERSHIP-17.9 € B Health-8033M€ Demographic change and wellbeing ICT Materials Food-4152M€ security, sustainable agriculture, marine and maritime research & the bio-economy Manufacturing Biotechnology Space Secure, clean and efficient energy- 3994M€ Access to risk finance 3538M€ Leveraging private finance and venture capital for research and innovation Transport- 6802M€ Smart, green and integrated Climate action- 3160M€ resource efficiency and raw Innovation in SMEs 619M€ Fostering all forms of inno - vation in all types of SMEs 3819 M€

H2020 is different • Broader topics • Strong emphasis on expected impact • Simplification: simplified list of types of action and funding rules • Funding rates: One project = one rate • Same funding level to all participating entities

H2020 Industrial Leadership Pillar KETs • Partnership with Industry to recover from economic crisis • Emphasis on R&D and innovation with strong industrial dimension • Involvement of industrial participants and SMEs to maximize exepcted impact => key aspect of proposal evaluation • Funded projects will be outcome oriented, developing key technology building blocks and bringing them closer to market • Key Enabling Technologies (KETs)

H2020 Industrial Leadership Pillar KETs • KETs – 6 Key Enabling Technologies, whose successful deployment by industry will strengthen Europe's industrial productivity and innovation capacity • Nanotechnology • Advanced Materials • Advanced Manufacturing & Processing • Biotechnology • Micro- and Nano-Electronics • Photonics • H2020 goal is to boost the deployment of industrial technologies (ensure their best use, capture market share, and enable innovative solutions to societal challenges)

H2020 Key Enabling Technologies (KETs) - Objectives • The 6 KETs are covered by 2 different Work Programs • 1. NMPB • Nanotechnology • Advanced Materials • Advanced Manufacturing & Processing • Biotechnology • 2. ICT • Micro/Nano-electronics, and Photonics • Photonics

H2020 KETs- Calls Characteristics • Use of Technology Readiness Level (TRL) • NMP in FP7: • TRLS 1-4 (up to 5-6 in 2012-13: pilots and demonstrators) • H2020 KETs: • TRLs from 3/4 to 7/8 (center at TRLs 5/6) • Two funding rates: • 100% funding: TRLs 3-6 • 70% funding: TRLs 5-7 • Non-profit participants can claim 100% funding • Cross-cutting KETs (comibnation of KETs and manufacturing)

H2020 KETs - Calls Characteristics • Two funding rates: • 100% funding: TRLs 3-6 • 70% funding: TRLs 5-7 • Non-profit participants can claim 100% funding • Cross-cutting KETs (combination of KETs and manufacturing) • Two funding rates: • 100% funding: TRLs 3-6 • 70% funding: TRLs 5-7 • Non-profit participants can claim 100% funding • Cross-cutting KETs (comibnation of KETs and manufacturing)

NMPB Work Program (2014-2015) • Publication date: 11th December 2013 • Indicative budget: 474.2 M€/ 2014, 504 M€/ 2015 • 2014 Submission Deadlines • NMP Call: • Single stage submission: 6th May 2014 • Two stage submission: 6th May 2014/ 7th October 2014 • Biotechnology Call: • Two stage submission: 12thMay 2014/ 26th June 2014 • * PPP Calls (FoF, SPIRE, EeB): • Single stage submission: 20th March 2014

Topics in the NMP Call (2014-2015) “Bridging the gap between nanotech. research and markets” • Goal: Addressing the next steps required towards deployment of innovation in nanotechnology and advanced materials • scaling up lab experience to industrial scale • demonstrating viability of manufacturing technologies • Topics examples: • Encapsulation technologies (for targeted delivery of drugs, cosmetic) • New applications • Production techniques, safety, standardization • Use of nanoparticles in 3D printing (AM- additive manufacturing) • Synthesis of nanomaterials for printing applications • Printing technologies for higher definition (down to nanoscale)

Topics in the NMP Call (2014-2015) “Nanotechnology and Advanced Materials for more effective Healthcare” • Goal: support more effective therapies for important diseases • Scope: R&D to reach point where “therapies can be considered fit for purpose” in preparation of (not including) clinical trail stages • Gender issues important: technologies and innovation should suit both women and men • Topics examples: • Biomaterials for the treatment of diabetes mellitus • Biomaterials for treatment &prevention of Alzheimer’s disease • Nanomedicinetherapy for cancer

Topics in the NMP Call (2014-2015) “Nanotechnology and Advanced Materials for low carbon energy technologies and energy efficieny” • Goal: support increased use of renewable energy sources and improved energy efficiency • Scope: Demonstrate use of nanotechnology and advance material in practical applications; demonstrate technology readiness • Topics examples: • Innovative materials for storage of energy • Extended in-service life of advanced functional materials in energy technologies (capture, conversion, storage, transmission of energy) • Materials innovations for optimisationof cooling in power plants • Post-lithium ion batteries for electric automotive applications

Topics in the NMP Call (2014-2015) “Exploiting the cross-sector potential of Nanotechnologies and Advanced materials” • Goal: Advancing the technological readiness of solutions that can be of usedin multiple applications and economic sectors • International cooperation appropriate • Topics examples: • Materials for severe operating conditions • Widening existing materials models • Fibre-based materials for non-clothing applications • Solutions for drinking water production (lower energy) • Materials-based solutions for restoration/preservation of European cultural heritage *ancient architecture, works of art)

Topics in the NMP Call (2014-2015) “Safety and Regulation” • Scope: Develop methods, techniques and equipment for: • materials characterisation & hazard identification • occupational exposure assessment • risk reduction and mitigation • International cooperation encouraged (in particular with: US, Canada, Australia, Korea, Japan, China, Brazil) • All projects should align with the EU Nanosafety Cluster • Topics examples: • Environmental fate of nanomaterials(testing & modeling) • Next-gen tools for testing and calibration of risk of nanomaterials

Topics in the NMP Call (2014-2015) “Standards, models and infrastructure” • Addressing general, structural needs in areas including: • Infrastructure • Metrology and standards • Skills and networking • Business models • International cooperation encouraged • Topics examples (CSA): • The Materials "Common House“ – debate forum • Societal engagement on responsible nanotechnology

Topics in the BiotechnologyCall (2014-2015) “Cutting-edge biotechnologies as future innovation drivers” • Goal: • Development of emerging tools (synthetic biology, bioinformatics…) • Convergences with other enabling technologies (e.g. nanotechnology -> bionantechnology; ICT -> bioelectronics) • Transfer & implementation into new applications (biosensors, biochips, drug delivery systems) • Topics • Synthetic biology: innovative approaches fo construction of organisms (*aiming for industrial products; **ethical issues) • New bioinformatics approaches

Topics in the BiotechnologyCall (2014-2015) “Biotechnology-based industrial processes” • Goal: • Enabling industry (chemical, health, mining, energy, paper, textile, food) to develop new products based on biotechnology • Biotechnology for detecting/monitoring/removing pollution • Note: additional topics specific to Food, Agriculture, Marine, and Forestry are under the Societal Challenge 2 call • Topics: • Enzymatic processes for industrial application (development of specific robust biocatalysts). • Downstream processes (which overcome the low/complex productivity of bioprocesses)

Topics in the BiotechnologyCall (2014-2015) “Innovative and comptitiev platform technologies” • Goal: • Develop platform technologies (eg genomics, meta-genomics, molecular tools…) • Terrestrstrial and marine biodiversity for novel applications • Biotechnology-based healthcare solutions (diagnostics, biological, bio-medical devices) • Topics: • Metagenomics as innovation driver

RI Work Program (2014-2015) • Publication date: 11th December 2013 • Indicative budget: 279 M€/ 2014, 304 M€/ 2015 • 2014 Submission Deadlines (all single stage) • New infra development ; Integrating and Opening Research Infrastructure: 2ndSep 2014 • E-Infrastructure: 15th April 2014 • Human Resources, Policy, International Cooperation: 14th May 2014

Research Infrastructures in H2020 • Definition for “Research Infrastructures”: • Facilities, resources, organizational systems and • services that are used by the research communities • to conduct research and innovation in their fields • This includes: • Major scientific equipment(or sets of instruments); • Knowledge-basedresources (collections, archives, scientific data) • e-Infrastructures (data, computing and software systems); • And…any other infrastructure of a unique nature essential to achieve excellence in research and innovation

Research Infrastructures in H2020 • Goals of the European RI program: • To open access to research infrastructures existing in the individual Member State to all European researchers • To avoid duplication of effort and to coordinate and rationalisethe use of these research infrastructures • To trigger the exchange of best practice, and develop interoperability of facilities and resources • To help pooling resources so that Europe can acquire and operate research infrastructures at world level • To connect national research communities, and become an international partner

The H2020 RI Work Program (2014-2015) • WP composed of 4 sections: • Developing the European RIs for 2020 and beyond • Developingnew world-class RIs • Integrating and opening national RIs of pan-European interest • Development, deployment and operation of ICT based e-Infrastructures • Fostering the innovation potential of RIs • Human Resources , Policy, International Cooperation

Topics in the RI Work Program (2014-2015) “Developing new world-class RIs “ • Goals: • Support the implementation, long term sustainability and efficient operation of research infrastructures identified by ESFRI • Identification of the next generation of new research infrastructures • Support provided for: • Conceptual and technical design of new research infrastructures (a bottom-up approach) • Preparatory phases, implementation and operation of prioritised ESFRI projects (notably ERICs)

Topics in the RI Work Program (2014-2015) 2. “Integrating and opening national RIs“ • Funding to support a consortium of several research infrastructures in a given field and a specific topic • can include other stakeholders (e.g. public authorities, technological partners) • “Starting Communities” (5M euros) / “Advanced Communities” (10M Euros) • Funding for: • Networking activities, standardization, establishing a common access procedure • Trans-national access or virtual access activities; • joint research activities to improve the integrated services provided by the infrastructures • Covering: Biological and Medical Sciences, Energy, Environmental and Earth Sciences , Mathematics and ICT, Engineering, Material Sciences , Physical Sciences , SSH)

Topics in the RI Work Program (2014-2015) 2. “Integrating and opening national RIs“ • Example • Biological and Medical Sciences - Starting Communities • Health information, clinical data, samples and medical images • New tools and resources for analysing and integrating genomic, epigenomic, proteomic, metabolomic and phenomic data. • Nanomedicinecharacterisationinfrastructure • Research infrastructures supporting rare diseases research • Biological and Medical Sciences - Advanced Communities • High-containment biosafety facilities and virus collections including for high-risk animal/human pathogens. • Vaccine infrastructures • Research Infrastructures for translating research on biological structures into innovation in biomedicine. • Research infrastructures in aquaculture.

Topics in the RI Work Program (2014-2015) 3. “e-Infrastructures“ • Goal: • Integrating e-infrastructure resources and services across all layers (networking, computing, data, software, user interfaces), in order to provide seamless services tailored to user needs. • Integration by deploying common/interoperable core services • Focus on: Big Data, Open Access, High Power Computing (HPC) • Topics examples: • Pan-European HPC infrastructure and services • Managing, preserving and computing with big research data • e-Infrastructure for Open Access • Centres of Excellence for computing applications

Topics in the RI Work Program (2014-2015) 4. “Support to innovation, human resources, policy and international cooperation • Topics examples: • Strengthening the human capital of research infrastructures • New professions and skills for e-infrastructures • Policy measures for research infrastructures • International cooperation for research • e-Infrastructure policy development and international cooperation

ESFRI – European Strategy Forum on Research Infrastructures • Set up by the EU Council of Research Ministers in 2002: Representatives of Ministers of all FP member states • Goal: support the development of a European policy for Research Infrastructure and discuss a long term vision at European level • Mandated to develop a strategic roadmap identifying new pan-European Research Infrastructures or major up-grades to existing ones • First Roadmap published in 2006, followed by two updates in 2008 and 2010

ESFRI – European Strategy Forum on Research Infrastructures ESFRI ROADMAP 2010

ISERD Program managers • Nanotechnologies, Materials, Biotechnology and Production; Transport (Incl. Aeronautics); Space; Medical Devices; Research Infrastructures : Dr. Nili Mandelblit, nili@iserd.org.il • Health; Food Agriculture and Biotechnology; Environment; Energy : Ms. Ayala Karniol, ayala@iserd.org.il • Information Communication Technology; Security : Dr. Aviv Zeevi, aviv@iserd.org.il • Marie Curie Fellowships; ERC; Socio-economic sciences and humanities; Science in Society : Ms. Smadar Hirsh, smadar@iserd.org.il • Bilateral programs with East Europe: Mr. Uzi Bar Sadeh,uzi@iserd.org.il • Bilateral programs with West Europe: Mr. Ran Arad,ran@iserd.org.il • Enterprise Europe Network (EEN) Mr. Uri Fishelson,uri@iserd.org.il

Thank you for your attention For more information: Dr. Nili Mandelblit nili@iserd.org.il * www.iserd.org.il

המינהלת הישראלית למו"פ האירופי The Israel-Europe R&D Directorate