1 / 10

Leveraging the Electronic Health Record for Clinical Research

Leveraging the Electronic Health Record for Clinical Research. John P. Glaser, PhD Vice President and CIO Partners HealthCare July 21, 2008. A Vision for Personalized Medicine. EMR with clinical decision support. Facilitated translational research leading to Diagnostic discovery

marlow
Download Presentation

Leveraging the Electronic Health Record for Clinical Research

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Leveraging the Electronic Health Record for Clinical Research John P. Glaser, PhD Vice President and CIO Partners HealthCare July 21, 2008

  2. A Vision for Personalized Medicine EMR with clinical decision support • Facilitated translational research leading to • Diagnostic discovery • Drug development Improved individualized medicine & pre / post symptomatic disease management Integrated genomic and phenotypic data repository Genomic research with high capacity IT

  3. Partners Personalized Medicine Infrastructure Research Clinical I2B2(HIVE / RelNet /Pharmacologic Surveillance) Clinical Decision Support Rules Engine Shared Pathology Information Network (SPIN) Computational Cluster and Storage Resources Electronic Health Record (EHR) EnterpriseTissue Banking Infrastructure Genomic Variant Interpretation Engine (GVIE) Consent Tracking System (CTS) Genomic Knowledge Base (GeneInsight) Enterprise LIMS Superstructure (GIGPAD / PowerPath) Research Patient Data Registry (RPDR)

  4. i2b2 Hive

  5. Can SSRI Response be Predicted?

  6. Costs of “High Throughput” Clinical Research

  7. Post Market Medication Surveillance Brownstein, PLoS ONE, 2007

  8. Fully Genetics Enabled EHR Architecture Clinician Systems Enterprise Service Bus LMR Decision Support Event/Workflow Engine Patient Data Warehouse CPOE Patient Genome Browser Genetics Runtime Services Data Access Assessment Engine Knowledge Access Result Receiver Master Order Catalog Genetic Test Coverage Patient Genetic Profile PEPR Family History, Genetic-based Problems Genetics Reference & Authoring Svcs. GVIE PEAR Genetic-based Drug Allergies Bus. Rules Mgmt. Sys. Gene Insight Ensemble CDR Genetic Test Reports VariantWire State Mgmt. Genetic Assessments To Pt Data Warehouse GMR Genetic Markers

  9. Organization • Harvard Partners Center for Genetics and Genomics • Scientific leadership • Laboratory operations • Initiated with $50M Harvard Medical School/Partners commitment • Informatics for Integrating Biology and the Bedside • Medical informatics and bioinformatics core • $20M/5 Year NIH funding • Partners Information Systems • Software development • Research Patient Data Registry • $5M annual operating budget • Industry sponsorship • HP • Affymetrix

  10. Governance • HPCGG • Scientific Director reports to the Dean, HMS and CEO, Partners • External Advisory Board • Information Technology • Quarterly meeting with Partners CEO, VP – Academic Affairs, and CEO, Physician Network • Bi-monthly IT operations meeting

More Related