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Objective: Understand the process of Translation

Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA, polypeptide. DO NOW: What is the mRNA strand that would be copied from this DNA strand? A T G A A C G G C T G T G T A C T A C G T

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Objective: Understand the process of Translation

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  1. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA, polypeptide DO NOW: What is the mRNA strand that would be copied from this DNA strand? A T G A A C G G C T G T G T A C T A C G T mRNA _____________________________________________________________ U A C U U G C C G A C A C A U G A U G C A

  2. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA, polypeptide 1. Label the molecules below as: mRNA, tRNA, ribosome, and amino- acids. Amino acid attachment site Amino - acid rRNA Ribosomal RNA anticodon tRNA Transfer RNA codon mRNA messenger RNA 2. Label the following parts: codon, anticodon, amino acid attachment sit on the molecules.

  3. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA, polypeptide http://www.bioplek.org/animaties/moleculaire_genetica/transcriptie.html http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter15/animations.html# www.PHSchool.com Web code: cbp-4123

  4. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA, polypeptide A B D C F E

  5. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA, polypeptide Arrange the following sentences in order to describe translation from mRNA to proteins • A. A second tRNA links to a second codon in the mRNA • B. Many amino acids bind together and make a poplypeptide (Protein) • C. Stop codon indicates the end of translation • D. The first and second amino acids bind together • E. A third tRNA brings a third amino acid to the ribosome • F. The first tRNA without amino acid leaves the ribosome • G. The ribosome binds to a mRNA strand at the start codon (AUG) • H. tRNA brings the first amino acid to the ribosome

  6. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA • The ribosome binds to a mRNA strand at the start codon (AUG) tRNA brings the first amino acid to the ribosome A second tRNA links to a second codon in the mRNA • The first and second amino acids bind together • Many amino acids bind together and make a protein • Stop codon indicates the end of translation • The first tRNA without amino acid leaves the ribosome • A third tRNA brings a third amino acid to the ribosome

  7. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide • Do Now: • List 4 things you learned about Translation: • What is the goal of Translation? • Where does it happen? • Which molecules and organelle(s) play a role in Translation? • Which molecules are produced?

  8. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide “I love Genetics”

  9. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide 1st base in codon

  10. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide 5. Using the Genetic Code Table, determine the order of amino acids established by the mRNA. A U G C U C A G C G U U A C C U A A __________________________________ A U G U C A G C G C C A C G A U A G __________________________________ A U G C A G C G U U A C C A U U G A __________________________________ Met – Leu – Ser – Val – Thr - Stop Met – Ser – Ala – Pro – Arg - Stop 1st base in codon Met – Gln – Arg – Tyr – His - Stop

  11. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide 1st base in codon C T A A U G A G C A A G C C U U U U A C U G A U Met – Ser – Lys – Pro – Phe – Thr - Asp

  12. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide 1st base in codon • Write the base sequence that would appear on an mRNA stand after transcription of the upper DNA strand: mRNA: ___________________________________________________________________________ Use the Genetic Code Table to determine the order of amino acids in the resulting protein fragment Amino Acids: _______________________________________________________________________ A G G U U A C C G A A U A A A C G U Arg – Leu – Pro – Asn – Lys - Arg

  13. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA Replication DNA Transcription mRNA Translation Protein

  14. Objective: Understand the process of Translation Key Words: translation, codon, anticodon, mRNA • Arrange the following sentences in order to describe the process of protein synthesis. • a. Ribosome translate mRNA into a protein • b. Protein shape determines protein function • c. mRNA leaves the nucleus • d. Transcription of DNA into mRNA • e. Amino-acid sequence determines protein shape

  15. Objective: Understand How the Genetic Code Works Key Words: translation, codon, anticodon, mRNA, bases, polypeptide • Do Now: • Transcription and Translation are two processes involved in protein synthesis. • Compare and contrast Replication, Transcription and Translation. • For each process explain: • Where does it occur? • What is the goal? • Which molecules and organelles are involved? • What molecule is produced? • How do nitrogen bases pair? A – T T – A C – G G - C DNA Helicase DNA polymerase Ligase Make identical copies of DNA Nucleus DNA A – U T – A C – G G - C Transfer information from DNA to ribosomes DNA mRNA RNA polymerase Nucleus mRNA Ribosome mRNA tRNA Amino-acids A – U U – A C – G G - C Ribosomes in cytoplasm or ER Proteins or Polypeptides Synthesis of proteins

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