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Biophysics of excitable cells

Biophysics of excitable cells. Multiple exitatory and inhibitory synaptic contacts allow complex neuronal interconnects. Cell-Semiconductor-Hybrids: Neuron on the Chip. More: Fromherz MPI Martinsried.

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Biophysics of excitable cells

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  1. Biophysics of excitable cells BPZ§4.1

  2. Multiple exitatory and inhibitory synaptic contacts allow complex neuronal interconnects BPZ§4.1

  3. Cell-Semiconductor-Hybrids: Neuron on the Chip More: Fromherz MPI Martinsried BPZ§4.1

  4. The electrical activity of neurons results from the opening and closing of specific ion-channels proteins in the neuron plasma membrane BPZ§4.1

  5. Voltage-gated cation channels generate action potentials BPZ§4.1

  6. Membrane depolarizations spread passively only short distances BPZ§4.1

  7. Action potentials are propagated unidirectionally without diminution Movements of only a few Na+ and K+ ions generate the action potential BPZ§4.1

  8. Patch clamps permit measurement of ion movements through single channels BPZ§4.1

  9. Different patch clamping configurations BPZ§4.1

  10. Current flux through individual voltage-gated channels determined by patch clamping of muscle cells BPZ§4.1

  11. All five subunits in the nicotinic acetylcholine receptor contribute to the ion channel BPZ§4.1

  12. P segments form the ion-selectivity filter BPZ§4.1

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