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OCE Student Oral Presentation Competition. Smartphone-based Biomedical Human-Computer Interface. Daniel Shapiro; PhD Candidate. Spring 2011. DS: CARG 2011. Biomedicine Problem. Treatments for cognitive impairment:. Drugs: side effects, Cost/Rx $37.44 [6], 2.8M people in Ontario’s
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OCE Student Oral Presentation Competition Smartphone-based Biomedical Human-Computer Interface Daniel Shapiro; PhD Candidate Spring 2011
DS: CARG 2011 Biomedicine Problem Treatments for cognitive impairment: Drugs: side effects, Cost/Rx $37.44 [6], 2.8M people in Ontario’s public drug system [5]. Surgery: only for extreme cases Computer Assisted Cognitive Behavioral Therapy: Works! Cognitive Behavioral Therapy: $40-180/hr [4] carg.site.uottawa.ca
DS: CARG 2011 In Search of a Solutions Electrode Array facing tongue = Novel Stimulus BrainPort, Tang et. al., lots of others… • Novel stimulus is the key: Works better than software-only approach. • We opted to develop our own platform with smartphone integration. • Existing solutions focus on: • Aiding the blind, Sensory substitution, Lost balance carg.site.uottawa.ca
DS: CARG 2011 NEAR Overview collaborative play, real-time image acquisition Industry Partner: NorDocs Technology Inc. Internet carg.site.uottawa.ca
DS: CARG 2011 What’s Happening? 4th prototype (32x32 array) 3rd prototype (8x8 array) 2nd prototype (8x8 array) 1st prototype (5x5 array) April 2011 Sept 2011 Jan 2011 [2] Sept 2010 Integrated Driver Board and Electrode Array Driver Board Driver Board carg.site.uottawa.ca
DS: CARG 2011 Value Proposition • We estimate the accessible market opportunity in the cognitive impairment market in Canada to be $1.75 bn/yr. • Estimated manufacturing cost of $100 per device • Existing solutions are not as flexible as an integrated platform • Cash raised = $350K + OCE matching • Currently TPS Lite, working on Collaborate application and MITACS-accelerate • Projected revenue • $1 million 2012 • $3 million 2013 • $10 million 2014 carg.site.uottawa.ca
DS: CARG 2011 Market Readiness Provisional patents are in the works R&D moving quickly towards 2011 human trials FDA - Sec. 882.1320 Cutaneous electrode. Class II (performance standards). [7] 510(k) application in 2012 Health Canada application in 2011 [8] Ethics application for trial in Ottawa on healthy subjects – Approval for Summer 2011 fMRI and inpatient trials Jan 2012 carg.site.uottawa.ca
DS: CARG 2011 References M. Ptito, et al., “Cross-modal plasticity revealed by electrotactile stimulation of the tongue in the congenitally blind”, Brain, vol. 128, no. 3, pp. 606-614, 2005 A. Borisenko, L. Monczak, I. S. Samra, O. Draghici, D. Shapiro, V. Groza, “A Low Cost Bidirectional Human-Computer Interface,” Medical Measurements and Applications (MeMeA), Apr. 2010. H. Tang, D.J. Beebe, "An oral tactile interface for blind navigation," Neural Systems and Rehabilitation Engineering, IEEE Transactions on , vol.14, no.1, pp.116-123, March 2006. http://www.camh.net/care_treatment/resources_clients_families_friends/challenges_and_choices/challenges_choices_abouttherapy.html http://news.ontario.ca/mohltc/en/2010/04/expanding-access-to-affordable-drugs.html http://www.theannals.com/cgi/content/abstract/36/9/1375 http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=882.1320 http://www.hc-sc.gc.ca/dhp-mps/md-im/applic-demande/guide-ld/applabel_demmarque_priv-eng.php carg.site.uottawa.ca