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BLAST Chemistry – an orthogonal approach to MedChem and Combichem. Traditional Medicinal Chemistry. Trapped in a synthetic route. BLAST Chemistry. Add convertible hooks. Change hooks to other groups. Promiscuously Modify using a Shotgun Approach.
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BLAST Chemistry – an orthogonal approach to MedChem and Combichem Traditional Medicinal Chemistry Trapped in a synthetic route BLAST Chemistry Add convertible hooks Change hooks to other groups Promiscuously Modify using a Shotgun Approach Limited ability to modify core restricted by available building blocks Combinatorial Chemistry
