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The study of biomolecules:. What is Biochemistry?. The chemistry of life!. What is Biochemistry?. The chemistry of life!. The study of biomolecules:. Structure. Properties. Interactions. Reactions.
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The study of biomolecules: What is Biochemistry? The chemistry of life!
What is Biochemistry? The chemistry of life! The study of biomolecules: Structure Properties Interactions Reactions Biochemists want to understand everything about all the molecules of life. This is a big job!
Life is diverse and complex! There are millions of different species on earth Each contains thousands of different types of molecules
Biochemists take advantage of similarities Different species are related; they evolved from a common ancestor Biomolecules and biochemical systems from different species are related
Biochemists take advantage of similarities Many biomolecules are complex polymers of basic units Protein (Polypeptide) Carbohydrate (Polysaccharide) DNA molecule amino acid units monosaccharide (sugar) units nucleotide units (sugar + phosphate + base)
Human cells are ~10 μm in length(~1000x shorter than your finger tip) Figures from “The Machinery of Life” by David Goodsell
Macromolecules are ~10 nm in length(~1000x shorter than the length of a cell) Figures from “The Machinery of Life” by David Goodsell
Organic molecules are ~10Å (1nm) in length (~10x shorter than macromolecules) Figures from “The Machinery of Life” by David Goodsell
Cells are crowded full of biomolecules (( in rapid, chaotic motion )) E. coli cell (30,000×) Cytoplasm (1,000,000×) Cell Wall (1,000,000×) Carb. Protein mRNA tRNA Ribosome DNA Figures from “The Machinery of Life” by David Goodsell