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Virus: Microlife Infectious Diseases. Objective: you will be able to understand and explain how viruses attack and effect human cells. Intro: Infectious Disease Terms. Disease which travels easily from one organism to another: Can also travel between species as well
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Virus: Microlife Infectious Diseases Objective: you will be able to understand and explain how viruses attack and effect human cells
Intro: Infectious Disease Terms • Disease which travels easily from one organism to another: Can also travel between species as well • Pandemic – fast spreading international outbreak • Epidemic- wide spread out break of disease at a specific location Asian Bird Flu 2007
Pathogen • Pathogen- Any organism that causes diseases • Carrier- any human giving a disease to another human • Vector- any NON-HUMAN source of a disease being passed on to a human • Diseases are primarily responsible for damaging individual cells, which causes us “sickness” symptoms” as cells break down • Ex: sore throat
4 Forms of Pathogens • Virus • Bacteria • Fungi • Protists Bacteria
Viruses • Non- Living: Do not require any energy to survive; No food/gas needs • Extremely Small Organism made up of DNA or RNA and a Protein Coat : CAPSID • Only capable of reproducing itself by “hi-jacking” another cell HIV Virus
3 Main forms of Viruses • (Norovirus) /Polyhedral • Bacteriophage • (Filovirus)/ Rod Shaped )
All viruses have two types of infection cycles • Lytic Cycle (Active) show signs of sickness immediately • Lysogenic Cycle (Non Active) no illness creates “provirus cells” within body then becomes active
Lysogenic Cycle • Shows no disease symptoms, may carry virus for years • FACT: HIV can stay like this for over 10 YEARS!! • 1. Virus attaches to host • 2. Viral DNA integrates or combines with cells DNA; becomes a “provirus” cell • 3. As cell splits and divides virus replicates with cell creating more “provirus” cells • 4. Some trigger activates virus: become ill
Lytic Cycle • Show disease symptoms • Virus actively attacking cells • 1. Virus attaches to host cell • 2. Virus enters host cell • 3. Virus destroys host cell’s DNA, replaces DNA with its own VIRAL DNA • 4. “Hijacked” cell creates more Viral DNA and protein coating • 5. Lysis-host cell ruptures and releases hundreds of new virus to attack more cells
Common Viruses • Chicken pox • Herpes • HIV • Ebola • Epstein Bar (mono) • Mumps • Warts • Influenza • Hepatitis • Common Cold