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Sirolimus: Preventing Organ Rejection, Treating Lung Disease, and Coating Stents

Looking for the best Sirolimus component, look no further than MedicaPharma. Sirolimus (rapamycin) is a powerful macrolide compound that plays a vital role in preventing organ rejection after transplants, treating lymphangioleiomyomatosis, and providing stent coating for cardiac health. Its primary immunosuppressive mechanism targets the mechanistic Target Of Rapamycin (mTOR), inhibiting B and T cell activation by reducing sensitivity to interleukin-2. Approved by the FDA in 1999, Sirolimus is marketed as Rapamune by Pfizer.

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Sirolimus: Preventing Organ Rejection, Treating Lung Disease, and Coating Stents

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Presentation Transcript

  1. Sirolimus: A Versatile Macrolide Compound for Organ Transplantation, Lung Disease, and Cardiac Health

  2. Introduction

  3. Mechanism of Action

  4. Medical Uses

  5. History and Discovery

  6. Research Studies • Tuberous sclerosis complex: Sirolimus shows promise in treating benign tumor growth. • Lymphatic malformation: Topical rapamycin improves symptoms. • Longevity: Sirolimus inhibits aging in various organisms. • SARS-CoV-2: Potential role in reducing cytokine storms and viral replication.

  7. Adverse Effects • Common reactions: Headache, nausea, diarrhea, fever, urinary tract infection, anemia, and more. • Adverse conditions: Diabetes-like symptoms, lung toxicity, reduced immune system function, increased cancer risk, impaired wound healing.

  8. Additional Medical Applications

  9. Conclusion

  10. Thank You for Visit

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