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Section III: GI Symptoms. Anorexia and cachexia Constipation Diarrhea Nausea/vomiting. Anorexia and Cachexia. ANOREXIA Loss of appetite, usually with decreased intake CACHEXIA Lack of nutrition and wasting Wholihan & Kemp, 2010. Causes of Anorexia and Cachexia. Disease related
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Section III: GI Symptoms • Anorexia and cachexia • Constipation • Diarrhea • Nausea/vomiting
Anorexia and Cachexia • ANOREXIA • Loss of appetite, usually with decreased intake • CACHEXIA • Lack of nutrition and wasting Wholihan & Kemp, 2010
Causes of Anorexia and Cachexia • Disease related • Psychological • Treatment related
Assessment of Anorexia and Cachexia • Physical findings • Impact on function and QOL • Calorie counts/daily weights • Lab test • Skin breakdown Coyne, 2007; Wholihan & Kemp, 2010
Treatment of Anorexia and Cachexia • Dietary consultation • Odor control • Medication • Artificial nutrition & hydration • Counseling
Constipation • Infrequent passage of stool • Frequent symptom in palliative care • PREVENTION IS KEY!
Causes of Constipation • Treatment related • Opioids • Other medications • Disease related • Obstruction • Hypercalcemia • Neurologic • Inactivity
Assessment of Constipation • Bowel history • Abdominal assessment • Rectal assessment • Medication review
Treatment of Constipation • Medications • Dietary/fluids • Other approaches
Diarrhea • Frequent passage of loose, nonformed stool • Effects • Fatigue • Caregiver burden • Skin breakdown
Assessment of Diarrhea • Bowel history • Medication review • Infectious processes
Treatment of Diarrhea • Treat underlying cause • Dietary modifications • Hydration • Pharmacologic agents
Nausea and/or Vomiting • Common in advanced disease • Assess etiology • Acute, anticipatory or delayed? • Causes physical and psychological distress
Physiological GI Metabolic CNS Psychological Disease related Treatment related Other Causes of Nausea and Vomiting
Assessment of Nausea and Vomiting • Physical exam • History • Lab values
Pharmacologic Treatment of Nausea and Vomiting • Anticholinergics • Antihistamines • Steroids • Prokinetic agents • Other
Non-Drug Treatment ofNausea and Vomiting • Distraction and/or relaxation • Dietary • Small/slow feedings • Invasive therapies