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Infection After ACL Reconstruction. H. Makhmalbaf MD Consultant Orth.& Knee Surgeon Mashhad University of Medical Sciences. Prevention:. Patient selection : phenotype, BMI Environment, surgical technique, experience Timing of surgery, duration of operation Antibiotic prophylaxis
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Infection After ACL Reconstruction H. Makhmalbaf MD Consultant Orth.& Knee Surgeon Mashhad University of Medical Sciences
Prevention: • Patient selection: phenotype, BMI • Environment, surgical technique, experience • Timing of surgery, duration of operation • Antibiotic prophylaxis • Type of graft, sterilization method, instrument • Fixation materials, Bio absorbable or metallic
Risk factors • Previous surgery • Revision ACL surgery • Presence of metal-works • Simultaneous procedures: PCL rec. osteotomy • Type of graft, sterilization method, instrument • Implants used • Synthetic ligaments
Infection after ACL • Superficial or deep infection • Clinical findings • Synovial fluid analysis • Laboratory findings • Imaging: X-ray, MRI
Treatment options • IV Antibiotics • Arthroscopic washout & debridement • Open arthrotomy with preservation of graft • Arthrotomy and removal of graft & fixation material
Outcome of infection • Reoperations, hospitalization, costs, job loss • Pain, limitation of ROM, scars • Wasted quads, longer rehab period • Graft jeopardy or failure • Loss of playing season or athletic career
Conclusion • Stick to the principles • Patient selection • Clean operative environment • Operative technique, instruments • Graft selection & sterility • Iv antibiotics • Close observation & prompt intervention
Infection Following Arthroscopic Anterior Cruciate ReconstructionMAJ Daniel Judd et al.Arthroscopy J. April 2006
Purpose of study: • Review their cases & other reports to identify • Risk factors • Evaluate physical & lab. Findings • Compare different treatments & • Assess clinical outcomes
Results : • Retrospective study 1994- 2002 • 11 infections in 1615 pts. • Hamstring autograft, previous knee surgery • & Acl reconstructions • TibialAcl graft fixation with a post & washer • Associated with increased infection
The goals of treatment are • To protect the articular cartilage • To protect the graft • Timely initiation of treatment including • Joint lavage, debridement & antibiotics • Are essential to treatment • Graft & hardware retention is possible • Expedient graft & hardware removal
Septic Arthritis After Arthroscopic ACL Reconstruction, Wang C 2009Arthroscopy J
Diagnosis & treatment of septic arthritis • 1997-2007, 21pts. Out of 4068 • The most common symptoms were: • Fever, swelling, severe pain, tenderness & • Restricted motion • ESR, CRP &Fibrinogen levels markedly elevated
Septic arthritis after • Coagulase-neg. Staph was the most common • Both conservative & 0perative treatment were effective • Longer recovery time and IV antibiotic therapy in the conservative group
Conclusion: • Septic arthritis is rare but potentially devastating complication • Correct diagnosis relies on: • Clinical evaluation, Lab tests • Synovial fluid analysis & bacterial culture • Early diagnosis & prompt treatment • Arthroscopic debridement & irrigation & • Retention of ACL graft when still functional
Autograft contamination during preparation for ACL reconstructionMichael E Hantes, MD et al JBJS Am 2008
Comments : • BPB & Hamstring Autografts most commonly • Graft contamination during preparation • By surgical masks, gloves & instruments • Contamination of graft could be a risk factor • In septic arthritis ESR & CRP are elevated
Aim of study: • Chance of graft contamination • Association between contamination & infec. • Chance of contamination of BPB & Hamstring • Contamination & inflammatory blood markers • 30 pts. In each group • 3 specimens for culture • ESR & CRP checked preop. & 3, 7,20 days post
Results: • A high rate of contamination (12%) • Contamination rate was equal in two grafts • No association between contamination & elevation of ESR, CRP • More positive cultures in 2nd & 3rd specimens • Slight elevation of ESR & CRP in all pts. • No association between graft cont. & infection