1 / 17

PEPTIC ULCER DISEASE

PEPTIC ULCER DISEASE. I. Definition A. Breakdown of the mucosa of the UGI tract-non malignant 1. Lack of depth-erosion B. Imbalance between acidity (pH) and the mucosal barrier strength. II. Causes A. Helicobacter pylori B. Anti-inflammatory medications C. Idiopathic.

menefer
Download Presentation

PEPTIC ULCER DISEASE

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. PEPTIC ULCER DISEASE

  2. I. Definition A. Breakdown of the mucosa of the UGI tract-non malignant 1. Lack of depth-erosion B. Imbalance between acidity (pH) and the mucosal barrier strength

  3. II. Causes A. Helicobacter pylori B. Anti-inflammatory medications C. Idiopathic

  4. III. Treatment A. Regardless of cause, acid lowering medications B. Treat the underlying cause

  5. IV. Symptoms A. Epigastric pain B. Can decrease in intensity with duodenal location C. Nausea and Vomiting D. Gastrointestinal blood loss

  6. V. Diagnosis A. Endoscopy B. Radiology C. Serologic tests for H. Pylori

  7. GASTRIC CANCER

  8. I. Adenocarcinoma A. Precursors 1. Chronic Gastric Atrophy a. H. pylori-WHO b. Pernicious Anemia c. ? Chronic high salt diet d. ? Multiple other environmental factors

  9. 2. Smoking 3. Obesity 4. Alcohol-excess

  10. B. Symptoms 1. More intense than ulcer or gastritis 2. Weight loss 3. Anorexia 4. Anemia and bleeding

  11. C. Treatment 1. Surgery is only cure 2. CTX and XRT are only palliative

  12. ALD

  13. I. Diagnosis A. History 1. CAGE a. Cut down b. Annoyed c. Guilty d. Eye Opener

  14. 2. Family History 3. Frequent ED visits 4. Encounters with law enforcement 5. Difficulty with employment and relationships

  15. B. Physical Exam & Lab 1. Non-specific • C. Imaging Studies 1. Exclude other pathologies • D. Role of liver biopsy

  16. II. Treatment A. Prevention 1. Abstinence a. 5 year survival-15% B. Nutrition C. Alcohol Withdrawl D. Corticosteroids/pentoxifylline

  17. E. Complications 1. Fluid Overload a. Paracentesis 2. Gastrointestinal Bleeding a. Life-threatening emergency 3. Hepatic Encephalopathy a. Determine the cause

More Related