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genomics7

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genomics7

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  1. Fig. 1. Comparison of Salmonella genome sequences. Five Salmonella genomes were compared with the SalmonellaTyphimurium sequence. The blue bars represent regions that are >90% identical at the DNA level between each serovar and S. Typhimurium. Selected features are annotated on the S.Typhimurium genome: rrn, seven ribosomal RNA operons; fels-1, fels-2, gifsy-1 and gifsy-2, previously characterized phage; phage, previously uncharacterized prophage; SPI-1–5, previously identified Salmonella pathogenicity islands not present in Escherichia coli; tus, TerB-binding sites delimiting the terminus of DNA replication; ori, origin of DNA replication. The following loci are also identified: put(proline utilization); pur, (purine); trp(tryptophan); fad(fatty acid oxidation); his (histidine); srl(sorbitol utilization); ilv(isoleucine-valine); and met(methionine). Coordinates are given in base pairs (bp) and centisomes (Cs), and each mark on the ruler corresponds to 1% of the genome (i.e. 1 Cs). For the S.Typhi comparison, filled bars represent sequence that is arranged in the same orientation as S.Typhimurium, whereas open bars represent sequence that is in the opposite orientation. Hence, these bars graphically represent the rearrangements that have occurred between these two Salmonella serovars. Note that the S.Typhimurium and S.Typhi sequences are complete whereas the other sequences are partial sequences. Abbreviations: S. Tm: Salmonella Typhimurium; S. Ty: Salmonella Typhi; S. Pa: Salmonella Paratyphi; S. En: Salmonella Enteritidis; S. Du: Salmonella Dublin; S. Pu: Salmonella Pullorum.

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