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Resolving Conflicting Views on Evolutionary Patterns in Eukaryotes

Explore mutation rates, evolutionary processes, and genetic drift in populations. Learn about macroevolution and microevolution dynamics. Access data on beneficial mutations. Dive into the fusion of eukaryotic cells. Relevant sources provided for further study.

michaelcarpenter
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Resolving Conflicting Views on Evolutionary Patterns in Eukaryotes

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  1. Conflicting “True” trees

  2. Possible resolution: Eukaryotes are a fusion

  3. from M. Sogin

  4. Популяционнаягенетика - 1

  5. Эволюция: движение в пространстве состояний - МАКРОЭВОЛЮЦИЯ движение в пространстве ЧАСТОТ состояний - МИКРОЭВОЛЮЦИЯ Происходит в ПОПУЛЯЦИЯХ

  6. Факторы эволюции • мутации • отбор • половое размножение • генетико-автоматические процессы (генетический дрейф) • миграция

  7. Факторы эволюции • мутации • отбор • половое размножение • генетико-автоматические процессы (генетический дрейф) • миграция

  8. Мутации мутационное равновесие: • модель двух аллелей:

  9. Мутации мутационное равновесие: • модель двух аллелей:

  10. Мутации мутационное равновесие: • модель двух аллелей: • модель ∞ числа аллелей

  11. Data on mutation rates

  12. Data on mutation rates

  13. Data on mutation rates at 20 human loci where loss-of-function mutations cause Mendelian diseases. Because mutations occur regardless of their impact on fitness, these data probably also describe the rate of occurrence of beneficial and neutral mutations. Kondrashov Hum Mutat2003

  14. ≈109bp http://www.genomesize.com

  15. Petrov et al. Science2000

  16. Drosophila Laupata Petrov et al. Science2000

  17. Petrov et al. Theor Pop Biol2002

  18. Petrov et al. Theor Pop Biol2002

  19. К след.лекции:

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