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Figure 3 CALGB (Cancer and Leukemia Group B) 9221: Fatigue, dyspnea, and physical functioning, as recorded on the EORTC (European Organization for Research and Treatment of Cancer) questionnaire, of patients with myelodysplastic syndrome who crossed over from supportive care to treatment with azacitidine (5-Aza-C) (n = 30) Reprinted with permission from the American Society of Clinical Oncology. Silverman LR and Mufti GJ (2005) Methylation inhibitor therapy in the treatment of myelodysplastic syndrome Nat Clin Pract Oncol 2: S12–S22 doi:10.1038/ncponc0347