INTENSE PULSED LIGHT (IPL) IN DERMATOLOGY

1. INTENSE PULSED LIGHT (IPL) IN DERMATOLOGY Dr. Ruxandra Cutus Dr. Razvan Bucur Cabinet SANDERM-Cluj

2. Intensed pulsed light (IPL) systems are high intensity light sources which emit : • polychromatic light; • noncoherent light; • broad wavelength spectrum ( 515-1200 nm) • visbile light (white light)+ IR light • LASERS( Light Amplification by the Stimulated Emission of Radiation) emit : • monochromatic light (single wavelength) • coherent light • Light and LASER beams are all forms of electromagnetic radiation

3. Adjustable IPL’s parameters: • energy-Joule • fluence-Joule/cm2=density of energy • filters-550, 560, 640nm • pulses parameters:-number of pulses(1-5) • -pulse duration(2-7ms) • -pulse delay(1-300ms) • Light Absobtion in Tissue- by the two natural cromophores: hemoglobin(580 nm) and melanin(400-750nm) • Light Tissue Effects-Photothermolysis=the matching of a specific wavelength, pulse duration and filter to obtain optimal effect on a targeted tissue with minimal effect to surounding tissues • Examples: - hair removal • -vascular lesions-thermocoagulation • -pigmented lesions-photorejuvenation (+ dermal remodelling by activation of cytokine and growth factors+increased production of colagen 1)

4. Historical data: • 1976- Muhlbauer- first description of thermocoagulation of capillary hemangiomas and port-wine stains by means of polychromatic light • 1994-first market ready system, Photoderm( Lumenis Ltd., Israel) • -organised in programs • for hair removal-short (F I-II), medium (F II-IV) and long (F V-VI)-depending on Fitzpatrick types of skin • for skin rejuvenation(vascular pigmented lesions)-program 1 ( F I-II ); program 2( F II-IV ); program 3 ( F V-VI ) • -different heads with different filters(560, 595, 640, etc) allowing to treat different body areas, different depths of skin lesions, different Fitzpatrick phototypes, different target structures

5. INDICATIONS: • HAIR REMOVAL • -one of the most important indications of IPL • -photothermolysis induces damage to the hair follicle and hair shaft in anagen phase causing a long term interruption in the hair growth cycle • -for localised hypertrychosis; hairy grafts and flaps; hirsutism; aesthethic purposes • -6-8 treatments at 6 weeks interval Advantages: -quick spot size -little pain -efficiency (studies reveal 80-90% clearance rate after 4-8 treatments) -safe-few side effects Possible side effects: -transient erythema(2-48 hours ± oedema -late evanescent erythema -mild pain; purpura-1-3 days -crust formation; isolated vesicles -transient hyper/hypopigmentation -permanent scars are unlikely

8. 2.PIGMENTED LESIONS -café au lait macules -Ota’s, Ito’s naevus -Becker’s and Spillus naevus -seborhoeic keratoses -actinic keratoses -poikiloderma of Civatte -melasma -mottled pigmentation -epidermal lentigines -ephelides -lentigo solaris -postinflamatory hyperpigmentation Mechanisms-melanosomes damaged by photothermolysis→melanin aggregates→macrophage transport Advantages:-quick-1-5 sessions( frequent 1-3), 3 weeks apart ) -minimal disconfort -lunch-time treatments -efficiency -safety-minimal or no side effects -all facial and non-facial areas can be treated

11. 1. 2.

12. 3.BENIGN VASCULAR LESIONS • -cuperosis( eythemato-telangiectatic rosacea ) • -rosacea ( papulo-pustulous- demodex destruction ) • acne and erythema associated with acne • -essential telangiectasias • hemangiomas • poikiloderma of Civatte • leg telangiectasias ( red, under 1 mm diameter ) • venous malformations (ex. blue rubber bleb naevus) • erythematous stretch-marks

16. 4.SKIN REJUVENATION -non-ablative skin-rejuvenation or “subsurfacing”-rhytides -good effect( better when associated IPL+RF or IPL+IR ) -improvement in the quality of skin-no total resolution -Mechanism: dermal remodelling occurs through increasing collagen 1 deposits, with collagen reorganisation into parallel arrays of compact fibriles -general skin rejuvenation for face, neck, decoltaeum area: minimising the pores; coagulation of the dilated vessels; dissapearance of pygmentary spots

18. 5.SCARS • -very good results; IPL treats: • hypertrophic scars ( post trauma; post surgery; post combustion ) • atrophic erythematous scar ( post acne ) • keloids ( post trauma; post surgery; post combustion and so on )

19. 1.Acute episode 2.Keloids and Hypertrophic Scars ; Postinflamatory hyperpigmentation

20. 3.During the first treatments 4. End of the treatment

21. CONCLUSIONS: IPL treatments are: • successful and non-invasive means of treatment • a very good alternative to conventional therapeutic options • particularly useful for hair removal; cuperosis; scars and angiomas • low rate of side effects • high levels of patient satisfaction • because of the wide range of potential combinations of wavelength, pulse durations, pulse frequency and fluences, working with IPL is a complex matter (lack of proper legislation) • can be used for better results in aesthetic medicine in combination with: botulinum toxin, fillers, Nd:YAG LASERS ( especially for angiomas and telangiectasis ), microdermabrasion or chemical peeling, aesthetic surgery • the spectrum of possible indications is continuously increasing( ex: IPL+ aminolevulinic acid for treatment of actinic keratosis or superficial basal cell carcinoma)

22. THANK YOU!