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Pharmacy Management Market Update . Mona Chitre , PharmD , CGP Vice President, Pharmacy Management. Quiz. This “purple pill” helps your stomach not spontaneously combust after that late-night spicy dish you should not have eaten…. Quiz. Prozac Nexium Motrin Premarin. Quiz.
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Pharmacy Management Market Update Mona Chitre, PharmD, CGP Vice President, Pharmacy Management
Quiz This “purple pill” helps your stomach not spontaneously combust after that late-night spicy dish you should not have eaten…
Quiz • Prozac • Nexium • Motrin • Premarin
Quiz This pill helps you “when the moment is right.”
Quiz • Speed • Solodyn • Viagra • Caffeine Pills
Quiz This pill helps you climb out from under a rock to face the world.
Quiz • Allegra • Prozac • Zoloft • Diovan
Quiz You’ve done it all in one night: You’ve eaten spicy food. The moment is right. You’ve crawled out from under that rock. Now it’s time to say “night-night.”
Quiz • Ambien • Lunesta • Albuterol • Advair
Drug Costs and Use Increasing GREAT JOB!! …However this proves that the pharmaceutical companies have done a great job as well.
Pharmacy Management: Market Landscape • Impact of Prescription Benefits • Specialty Medications • Price Increases • Appropriate Care • Trend Management Opportunities
Why are Prescriptions important: • #1 Benefit:Most commonly used benefit • 67-70% use the drug benefit each year • 12-15 prescription fills per person per year • #1 Cost:Drugs are the top cost driver
How does Rx affect benefit plans? Medical Benefit Pharmacy Benefit Retail Pharmacy Mail Pharmacy Specialty Pharmacy Drug Cost : 20-25% of total health care cost ($75-$85 pmpm) • Hospital • Physician Office • Outpatient Facility • Clinics • Infusion centers • Home Infusion • DME • Drug Costs: 5-8% of total medical cost ($20-$25 pmpm)
Prescription Benefit Medical Benefit Cancer Rheumatology Psoriasis Contraceptives Multiple Sclerosis Osteoarthritis Asthma Pulmonary Arterial Hypertension Diabetes Antidepressants Hypertension Hyperlipidemia PPIs Glaucoma Hemophilia Vaccines Immunoglobulins Enzyme Replacement
Today’s pharmaceutical benefit reality $20 – generic Rx $200 – brand Rx $2,200 – specialty Rx
New Technology: Specialty Drugs General Description: • High Cost • Biologics • Pharmacy or Medical Benefit (Oral, Injectable, Infusion) • Monitoring Required • Targeted • Chronic or genetic conditions with still an unmet need
Specialty Drug: Employer Impact Employer: 200 employees (450 total with coverage) • 5300 Prescriptions/ year • Average employer cost/Rx: $60 • Total Annual Rx cost for employer: $320,000 Specialty Drug Impact: Tykerb • Oral drug used in combination for breast cancer. • Incremental Added Cost: $55,000/ year 15% increase in Rx expense that year
Specialty Drug: Employer Impact Large multiple employer coalition: • 41,000 covered lives • Medical Drug PMPM: $14.47 (07-08) • Medical Drug Trend: 50% over 2 years • Specialty Drug Impact: • 2 of the covered members treated with Fabrazyme • Annual cost of > $518,000 This drug accounted for 8% of the medical expense
“Cancer Trends Demand Call To Action” The Tipping Point Cost Trends “At Memorial Sloan-Kettering Cancer Center, we recently made a decision that should have been a no-brainer: we are not going to give a phenomenally expensive new cancer drug to our patients” • Zaltrapv. Avastin • Same Efficacy • $11,000 difference
More than 90 percent of cancer therapies approved in the last five years cost more than $20,000 for a 12-week course of therapy. Significant price increases in oncology products have not necessarily shown a correlation between overall survival or progression free survival.
Trend Management: Specialty • Pipeline Review and Planning • Use Management (to ensure safety and appropriateness) • Manufacturer Contracting (where applicable) • Waste Management • Collaboration with Specialists • Clinical Outreach: Adherence, Side Effect Management • Off-Label Use Management
Case Study: Multiple Sclerosis • New Technology: • 2010: 2 New agents - 1stCombination drug and 1stOral Agent • Significant Price Increases: • 2006 Price - $ 15,000 • 2010 Price - $37,000
Trend Management: GENERICS “Ask your doctor if a generic is right for you”
Employer Impact: Case Study • Employer: 200 employees (450 total with coverage) • Avg 12 Rx/person/yr: approx. 5,300 Rx • Avg employer cost/Rx: $60 • Generic Fill Rate: 65% (3,445 of the Rx are for generic) • Total Annual Rx cost for employer: $318,000 • Generic Opportunity: Increase GFR to 70% • 265 brand drug Rx changed to a generic option. • Cost saving per Rx: $100 • Savings to employer: $26,500 (8% of spend) • Savings to employee: 200-$400+/year Each 1 point increase in GFR can reduce Rx spend by 2-3%
Medication Errors – National Data • Medication Errors are estimated to account for $21 billion in wasteful medical spending annually. • Inpatient preventable medication errors cost $16.4 billion annually. • Outpatient preventable medication errors cost $4.2 billion annually. • 70% of Medication Errors occur due to prescription mistakes. • Dosing errors – 37% • Drug allergies or harmful drug interactions – 11% • Medication reconciliation errors during admission – 22% • Fragmentation of Care • Survey shows only 13% of primary care physicians communicated with a pharmacist regarding new prescriptions.6
Medication Non-adherence 50% of all prescriptions are not taken correctly • Human toll • About 125,000 preventable deaths/year • Diabetics: 699,000 ER Visits, 341,000 hospitalizations • Financial toll • Additional $290 billion dollars of health care costs • 13% of the total healthcare spend in this country • $8.3 billion in annual healthcare costs for diabetics
Adherence rates across conditions * 1 year after initiation of both antihypertensive and lipid-lowering therapies; proportion of days covered ≥80%. † 1 year after initiation of therapy; medication possession ration (MPR) ≥80%. ‡ MPR 80%-110% of days eligible for Medi-Cal. § MPR >80% for patients with at least 90 days of observation.
Trend Management: Adherence Improvement Social/ Economic Patient- related Therapy- related Condition- related HealthCare System The Five Dimensions of Non-Adherence*