70 likes | 197 Views
EBC-DARPA project: Contribution of Maastricht group. Elia Formisano, Federico de Martino, Giancarlo Valente, Rainer Goebel. Analysis of movie data. Standard analysis steps (BrainVoyager QX) Data-driven group ICA to define common patterns Training and optimization of SVM-based classifiers.
E N D
EBC-DARPA project: Contribution of Maastricht group Elia Formisano, Federico de Martino, Giancarlo Valente, Rainer Goebel
Analysis of movie data • Standard analysis steps (BrainVoyager QX) • Data-driven group ICA to define common patterns • Training and optimization of SVM-based classifiers
Standard fMRI data analysis steps Recorded time series (EPI) Anatomical images Coregistration offunctional andanatomical data SegmentationCortex reconstruction Correction of head motion Spatial and temporal filtering Spatial normalisation Statistical localization of brain activation, functional maps Single subject analysis Group analysis ITalairach space Group analysis II – Surface-based alignment
Data driven selection of the Region of Interest using self-organizing group ICA. Z=2.325 Cluster 1 Cluster 2 Cluster 3 Cluster 4 Cluster 5 Cluster 6 1 2 3 4 5 6 Esposito et al., Neuroimage 2005
Training of a Support Vector machines using features extracted from the time-courses of the voxels in the ROI. Voxel activity Voxel n Voxel 2 n time 2 Voxel 1 time 1 Feat. Vector 1 Feat. Vector 2
Classification of Brain States Voxel activity Voxel n Voxel 2 n time 2 Voxel 1 time 1 Feat. Vector 2