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CATH 3.40.630.10 (~7800 proteins)

SCOP Fold: Phosphorylase/Hydrolase-like fold Superfamily: 53187 (Zinc dependent exopeptidases). PFAM Clan CL0035: Peptidase_MH/MC/MF. 8 Pfam Superfamilies PF00246 : Zinc carboxypeptidase, Peptidase_M14 PF00883 : Cytosol aminopeptidase family, catalytic domain, Peptidase_M17

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CATH 3.40.630.10 (~7800 proteins)

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  1. SCOP Fold: Phosphorylase/Hydrolase-like fold Superfamily: 53187 (Zinc dependent exopeptidases) PFAM Clan CL0035: Peptidase_MH/MC/MF 8 Pfam Superfamilies PF00246: Zinc carboxypeptidase, Peptidase_M14 PF00883: Cytosol aminopeptidase family, catalytic domain, Peptidase_M17 PF01546: Peptidase family M20/M25/M40, Peptidase_M20 PF04389: Peptidase family M28 PF04952: Succinylglutamate desuccinylase / Aspartoacylase family PF05343: M42 glutamyl aminopeptidase, Peptidase_M42 PF02127: Aminopeptidase I zinc metalloprotease (M18) PF05450: Nicastrin 135 JCSG “HP” targets Background and Significance • MEROPS Peptidase DB • CLAN OF ASPARTIC PEPTIDASES • Peptidase_AACL0129Peptidase clan AA • Peptidase_ADCL0130Peptidase clan AD • CLAN OF CYSTEINE PEPTIDASES • Peptidase_CACL0125Peptidase clan CA • Peptidase_CDCL0093Peptidase clan CD • Peptidase_CECL0134Peptidase clan CE • CLAN OF METALLO PEPTIDASES • Peptidase_MACL0126Peptidase clan MA, Matrix metallopeptidases, drug targets, small molecule inhibitors • Peptidase_MDCL0170Peptidase MD • Peptidase_MECL0094LuxS/MPP-like metallohydrolase • Peptidase_MHCL0035Peptidase clan MH/MC/MF, 8 Pfams, CATH 3.40.630.10,Diseases roles? • Peptidase_MLCL0095Peptidase Clan ML • Peptidase_MXCL0150Peptidase Clan MX • CLAN OF MIXED (C, S, T) CATALYTIC TYPE • Peptidase_PACL0124Peptidase clan PA • Peptidase_SHCL0201Peptidase clan SH CATH 3.40.630.10 (~7800 proteins)

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