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Seasonal influenza vaccination in the WHO European Region preliminary results. WHO workshop on sentinel influenza surveillance, 16-17 November, 2011 Istanbul, Turkey. Pernille Jorgensen | Influenza and other Respiratory Pathogens WHO Regional Office for Europe
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Seasonal influenza vaccination in the WHO European Regionpreliminary results WHO workshop on sentinel influenza surveillance, 16-17 November, 2011 Istanbul, Turkey Pernille Jorgensen |Influenza and other Respiratory Pathogens WHO Regional Office for Europe In partnership with the VENICE Collaboration and ECDC
Background influenza vaccines • Influenza vaccines introduced 1940s • Vaccination is primary means of preventing influenza today • Excellent safety record • High efficacy:70-90% in healthy adults • …but lower in the elderly... • 60% in persons >60 years • 30-40% in persons >85 years
Priority groups for influenza vaccination • Elderly • Health care workers • Pregnant women • Residents of institutions for older persons and the disabled • Individuals >6 months with underlying chronic medical conditions Reference: WHO/Europe recommendations on influenza vaccination during the 2011-2012 winter season www.euro.who.int/__data/assets/pdf_file/0008/152297/EURO_2011_2012_flu_vacc_rec.pdf
First VENICE survey on seasonal influenza vaccination in WHO European Region
Aims and objectives Aim • To assess progress toward the WHO goal of 75% influenza vaccine coverage in elderly by 2010 Specific objectives • Identify country specific vaccine recommendations • Describe influenza vaccine coverage in 2008/2009 and 2009/2010 • Describe influenza vaccination implementation • Provide a baseline from which to measure future improvements in seasonal influenza vaccine uptake
Methods • Self-administered questionnaire to national vaccination focal points, 53 WHO Member States in August 2011
Preliminary results • Response from 46/53 (87%)
National influenza vaccination programmes • 43/46 (93%) countries had access to seasonal influenza vaccines in 2008/2009 season
Seasonal influenza vaccine doses available relative to total population • Range from <1% to 23% • Note: Limited vaccine availability may reflect risk group vaccination policies
National recommendationsfor vaccination seasonal influenza Clinical risk groups Elderly HCW hospital + outpatient Pregnancy
National recommendationsfor vaccination seasonal influenza Children
Principal outlets for administration of seasonal influenza vaccine & cost Cost of single dose vial or prefilled syringe (€) Primary health care clinics are most important site for seasonal influenza vaccination in 90% of countries Median: 5.1 EUR
Vaccine uptake in elderlyEU/EEA countries, 2008/2009 75% coverage target
Influenza vaccination coverageClinical risk groups, 2008-2009 N=6
Influenza vaccination coverage Health care workers, 2008-2009 N=9
Seasonal influenza vaccination campaigns • 81% produced specific information for public and health professionals • 73% made use of media campaigns • 93% TV • 93% News paper adds • 87% Radio • 73% Posters
Conclusions • Most countries in the Region have access to seasonal influenza vaccine • Similar recommendations for “traditional” risk groups in the Region • Only, 1 country reached WHO 2010 target of coverage >75% among elderly • Low coverage in health care workers • Cost of influenza vaccine very similar • Frequent use of media campaigns to promote influenza vaccination
Key challenges • Limited vaccine uptake monitoring • Difficult to monitor progress • Difficult to monitor impact • Low vaccine uptake • Limited vaccine access in some countries
Suggested readings www.who.int/wer/2004/wer7903.pdf • Hollmeyer HG et al: Influenza vaccination of health care workers in hospitals- a review of studies on attitudes and predictors. • Vaccine. 2009 Jun 19;27(30):3935-44. • Babcock H et al: Mandatory Influenza Vaccination of Health Care Workers: Translating Policy to Practice Clin Infect Dis. (2010) 50 (4): 459-464. • Mereckiene J et al: Differences in national influenza vaccination policies across the European Union, Norway and Iceland 2008-2009. • Euro Surveill. 2010;15(44)
Next steps -country plans • Change seasonal vaccine recommendations and include pregnant women and persons with morbid obesity • Prioritization of risk groups in settings with limited quantity of vaccines • Assessing cost-benefit of influenza vaccination programme in different settings • Evaluating vaccine uptake • Improve perception of influenza vaccines in the public
Sincere thanks to • All national focal points who provided the data • VENICE • Jolita Mereckiene • Suzanne Cotter • Luca Dematte • ECDC • Angus Nicoll • WHO • Anna Bolokhovets • Annemarie Wasley • Guido Maringhini - -