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Case Study #4. Dr .Garielle Wagnac, Dr.Aarti Patel Dr.Kimberley Hausheer, Dr.Pankhuri Garg. Patient History. 42 year-old male No major health issue to date Notable increase in weight over past month—gain of 17 pounds Recent lethargy
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Case Study #4 Dr.Garielle Wagnac, Dr.Aarti Patel Dr.Kimberley Hausheer, Dr.Pankhuri Garg
Patient History • 42 year-old male • No major health issue to date • Notable increase in weight over past month—gain of 17 pounds • Recent lethargy • Patient is on a new eating regimen—every meal is from a ‘fast-food’ restaurant
Physical Examination Laboratory Results Negative for hepatitis Excessive glycogen granules in liver High levels of fat in liver – abnormal fat metabolism Low testosterone levels Abnormal cell calcium balance • Enlarged Liver • Muscle Weakness
Diagnosis Smooth ER not properly functioning!
Smooth Endoplasmic Reticulum What it isn’t doing! Leads to……! (Uh Oh) Abnormal levels of calcium Muscles are getting weaker instead of being strong Low levels of testosterone Excessive glycogen granules present Presence of fat in liver past normal levels • Regulations of calcium concentration • Steroid metabolism • Metabolism of carbohydrates
What caused it? • The new diet contained a lot of fat. The liver could not metabolize all of the fat and as a side effect fat begins to build hurting the liver, which takes care of fat metabolism. • Once the smooth ER is down then everything goes south. • The gain of weight is due to diet and lethargy is caused because of the poor diet that the patient is undergoing.